Maryland-based ACUITYnano LLC develops biomedical and laboratory technologies that use microfluidics, optics, machine vision, and embedded control to manipulate and study nanoscale objects and living cells. Its R&D work ranges from a low-cost on-chip near-field optical microscope with reported 10-nanometer resolution to automated systems for cell and nematode analysis, including research designed for microgravity experiments. The company also helps research organizations, startups, and medical-device businesses move concepts from early development into prototypes and products.
Advanced NanoPhotonics, LLCAdvanced NanoPhotonics, LLC is a nanotechnology company whose work grows from deep experience in space-instrument engineering, including leadership on major NASA missions such as Hubble, Cassini, and the James Webb Space Telescope. Based in Lanham, Maryland, it develops carbon-nanotube technologies for space exploration and Earth-based applications, serving organizations that need specialized optical and nanotechnology research.HARWOOD, MD
AccuStrata IncFounded in 2008 through the University of Maryland TAP program, Rockville-based AccuStrata develops custom optical spectroscopy instruments, sensors and control systems for real-time industrial and environmental monitoring. Its fiber-optic platforms combine optical measurement with predictive modeling and machine learning, while the company takes projects from early concepts through prototypes, field validation and commercialization. AccuStrata’s patented work includes AtOMS, a system for monitoring thin-film deposition and etching, and the company has developed technology for applications ranging from solar manufacturing to portable water testing.ROCKVILLE, MD
Creatv BioPrivately held Creatv MicroTech, led by MIT-trained scientist and founder Cha-Mei Tang, is known for bringing diagnostics together with microfabrication to develop cancer research technologies. Its Creatv Bio division applies that expertise to blood-based liquid-biopsy research for cancer screening and treatment monitoring, including work with biopharma companies and clinical-trial sponsors. Creatv MicroTech received an R&D 100 Award in 2006 and was named Montgomery County’s Biotech Company of the Year in 2013.POTOMAC, MD
Diagnostic BiochipsFounded in Glen Burnie in 2013, Diagnostic Biochips develops neural probes and recording systems that let researchers measure brain activity inside intact organoids and other neural models. Its SomaFocus platform combines high-density silicon probes with automated depth recording, real-time analysis, and cloud-based data storage, extending electrophysiology beyond surface-level measurements. The company grew from technology developed at the University of Michigan and through Howard Hughes Medical Institute’s Janelia Research Campus, with more than $6 million in NIH and DARPA research funding.GLEN BURNIE, MD