Founded from Franco Kraiselburd’s early cell-therapy work at the University of São Paulo, Asclepii develops regenerative wound-care products, led by its FDA-cleared Poseidon™ nanosilver hydrogel. The company’s research links Cleveland’s Case Western Reserve University and global collaborators with a practical focus on making advanced wound treatment scalable and accessible. Its work builds on the regenerative-medicine legacy of Arnold Caplan, who mentored Kraiselburd and Asclepii colleague Miguel.
FDA-cleared
certification
Fesarius Therapeutics IncFounded in 2015 from tissue-engineering work at Weill Cornell Medicine, Fesarius Therapeutics develops regenerative medical devices for wound care and reconstructive surgery. Its flagship product, DermiSphere hDRT, is an FDA-cleared hydrogel dermal regeneration template designed to support treatment of full-thickness skin loss. The company was co-founded by plastic surgeon and Weill Cornell professor Dr. Jason Spector, whose clinical experience shaped the technology.NEW YORK, NY
NoxsanoFounded by scientists and healthcare professionals with experience at Procter & Gamble and McKesson, Noxsano is a wound-care company developing treatments for veterinary and human medicine. Its patented technology delivers nitric oxide at the wound site, with veterinary use serving as the company’s initial market before planned expansion into human care.CINCINNATI, OH
RashEndZ, IncFounded around the work of neonatal intensive-care nurse and co-founder Colleen John, R.N., RashEndZ, Inc. makes FDA-registered occlusive wound dressings that deliver continuous topical oxygen through standard medical oxygen supplies. Based in St. Petersburg with an executive office in New York City, the company’s patented GasPort™ platform is designed for hard-to-heal wounds as well as pediatric and perineal skin conditions, without proprietary equipment. Its clinical program includes an FDA-approved Florida hospital safety study and reported case results in pressure injuries and long-term-care wounds.BROOKLYN, NY
Aethl BioFounded in Pittsburgh, Aethl Bio develops science-driven solutions for chronic wounds, aiming to restore skin function rather than simply close the wound’s surface. The company’s patient-centered work focuses on durable healing and reducing recurrence, complications, and the long-term burden of nonhealing wounds.PITTSBURGH, PA