Founded in 1987 by former Johns Hopkins employees and students, Baltimore-based BME Systems Inc. provides electro-mechanical design, custom laboratory parts and software engineering for research and production in bioscience. The company designs and fabricates unusual laboratory components, including replacements for obsolete parts, and integrates hardware, instrumentation and software into working systems. BME Systems says it has supported medical and industrial bioscience R&D for 35 years, with some systems operating continuously for more than 25 years.