Founded by interventional neuroradiologist Bryan Pukenas, MD, and medical-device executive Kamna Giare-Patel, Cerespectus is a Philadelphia medical-device company focused on making central nervous system gene-therapy delivery safer and more accessible. Its developing Esperanza catheter is designed for targeted treatment delivery through lumbar access, with the aim of helping more physicians perform the procedure. The device is not FDA cleared or commercially available.
VentruFounded in Philadelphia in 2022 as a spin-out of the Penn Center for Innovation, Ventru makes the DIVE Guide, a device designed to help neurosurgeons place external ventricular drains more safely and accurately. The company was founded by neurosurgeons Rachel Blue and Michael Spadola after their early training exposed the limitations of freehand intraventricular access, alongside medical-device commercial veteran Bryan Humbarger. In a 50-patient IRB-approved study, Ventru reports a 100% drain-placement rate with an average of one catheter pass.PHILADELPHIA, PA
Lumenate MedicalLumenate Medical is developing a catheter-based cystoscope that lets non-urologist providers collect bladder images for remote review by board-certified urologists. Founded by a team that includes Johns Hopkins engineering and medical expertise, the Baltimore-based company is focused on shortening long waits for bladder cancer screening while keeping specialists in the decision-making loop. Its device remains in development and is not yet cleared or approved for sale by the U.S. Food and Drug Administration.
Camber Spine Technologies, LLCCamber Spine Technologies develops surgeon-designed medical devices for minimally invasive and minimally disruptive treatment of complex spinal conditions. Based just outside Philadelphia, the company combines 3D printing with its ENZA® and SPIRA® implant platforms and has developed a patented OLIF system for oblique access to the lumbar spine. Its 27,000-square-foot facility includes a mechanical test lab, prototype shop and double cadaver lab, and the company is an ISO 13485-certified medical device manufacturer.KING OF PRUSSIA, PA
B. Braun Interventional Systems IncPart of the B. Braun Group of Companies, B. Braun Interventional Systems develops medical devices with clinical users to address the practical needs of interventional care. Its work serves physicians, technologists, nurses and patients through devices intended to bring safety and precision to procedures.BETHLEHEM, PA