Founded in 1994, Chem-Master International is a privately held Hauppauge research, development and manufacturing company that provides contract work in organic and medicinal chemistry. Its scientist-owned team includes 14 full-time Ph.D. scientists and draws on 75 years of combined industrial and academic research experience. Operating from a 2,000-square-foot laboratory associated with Stony Brook University’s Long Island High Technology Incubator, the company develops custom compounds and scalable chemical processes for pharmaceutical, biotechnology and academic clients.
J&W PharmlabFounded in 2002, Pennsylvania-based J&W Pharmlab is a contract research organization that performs custom organic synthesis and medicinal-chemistry research for life-science clients. Its 10,000-square-foot laboratory combines PhD-led project work with proprietary chiral-resolution methods and a portfolio of more than 30,000 novel building blocks. All custom synthesis is conducted domestically, with clients communicating directly with the scientist assigned to their project.LEVITTOWN, PA
AstaTech, IncFounded in 1996 by former pharmaceutical-company scientists, Bristol, Pennsylvania-based AstaTech develops and manufactures drug-discovery building blocks and advanced intermediates while providing chemistry CRO/CDMO services. Its in-house team includes PhD chemists, and the company supports projects from discovery through commercial-scale manufacturing for 1,000 companies worldwide. AstaTech’s catalog includes more than 250,000 compounds, with custom synthesis available from milligram quantities through 10 kilograms and bulk manufacturing extending to ton scales.BRISTOL, PA
Teadus PharmaTeadus Pharma is a Hyderabad-based pharmaceutical company built around specialist chemistry and a scientific, research-led team. Its 20,000-square-foot R&D center brings together 60 chemists, while the company serves biotech startups, virtual biotechs and multinational pharmaceutical clients with custom chemical synthesis and development support. Teadus also maintains its own manufacturing unit and works with partner sites to help move projects toward commercial production.BERWYN, PA
Olon USAFounded in 1986 and acquired by Olon SpA in 2017, Olon USA is a contract research, development, and manufacturing partner focused on small-molecule drugs and other chemical-based industries. Its single 25-acre Concord, Ohio site brings together 160,000 square feet of laboratory and manufacturing space, with services spanning development through scale-up and production. The company reports that 71% of its chemists hold advanced degrees and that its quality system has supported audits by more than 200 clients and the U.S. FDA.CONCORD, OH