Since 1970, Columbus Instruments has designed and manufactured scientific instruments for monitoring behavior and physiology in laboratory animals, along with environmental research systems. Founded by Dr. Jan Czekajewski, the Columbus, Ohio company pioneered commercially available activity monitors and indirect calorimetry, later developing its Micro-Oxymax respirometer in response to EPA remediation research after the Exxon Valdez spill. Its in-house engineering team continues to build customizable instruments used by researchers worldwide, with more than 21,000 scientific citations.