Founded in 1985 by MIT- and Harvard-trained scientist Dr. Dean Hsieh, Conrex Pharmaceutical develops transdermal drug-delivery technology and therapeutic formulations. The company is best known for Permeation Enhancement Technology™ (PET™), its patented polymer-matrix system for temporarily helping larger active molecules pass through the skin, a platform used in the FDA-approved Testim® testosterone gel and in Conrex’s SESHA Skin Therapy line. After Dr. Hsieh’s death in 1995, his wife and co-founder, Phyllis Hsieh, became president and CEO and guided the company’s expansion into skincare.
FDA GRAS (Generally Recognized as Safe)
Compliance program
Drug Master File with FDA
Registration
Sesha Skin TherapyFounded in 1996 from biomedical research by Harvard- and MIT-educated scientist Dr. Dean Hsieh, Sesha Skin Therapy makes science-based professional skincare for everyday use. Its proprietary Permeation Enhancement Technology (P.E.T.®), developed over more than 30 years, is designed to carry active ingredients into the skin’s regenerative layers; the company’s U.S. lab and headquarters produce paraben-free, non-toxic products that are never tested on animals. Sesha also supports licensed estheticians through specialist treatments, products, and professional resources.WEST CHESTER, PA
Velius, LLCVelius, LLC is a research-driven biopharmaceutical company developing prescription and over-the-counter medicines that target or are delivered through the skin. Founded and built by medical professionals, the Great Neck company is led by a surgeon and a pharmacist and has built its portfolio around nanotechnology-enabled film delivery, including products for scar treatment and dermatological conditions. Its intellectual-property portfolio includes patents issued in more than 25 countries and a suite of 19 developed pharmaceuticals.GREAT NECK, NY
TRPL LLCBuilt around deep transdermal-drug-delivery expertise, TRPL LLC is a contract research laboratory developing and testing customized drug-delivery systems and products for pharmaceutical, over-the-counter, cosmeceutical, and nutraceutical companies. Its New York and New Jersey laboratories support formulation and product development, with particular strength in in-vitro percutaneous absorption studies and in-vivo models. The scientific team brings more than 75 years of combined experience, including leadership from a former Long Island University pharmaceutical-sciences professor who authored more than 100 research papers.PARAMUS, NJ
Topix Skin HealthFounded in 1981 by Stanley and Burt Shaffer, Topix Skin Health develops and manufactures science-based skin-care products through a portfolio of professional and consumer brands. Its New York-based Topiderm operation provides in-house research, development and manufacturing, supported by more than 40 scientists, including three full-time PhD microbiologists. The company’s formulas are developed with dermatologists and physicians, with products tested by more than 6,000 physicians over four decades.AMITYVILLE, NY