Founded by scientists from Karolinska Institutet and the Feinstein Institute for Medical Research, Cymbathera AB develops a non-invasive bioelectronic medical device for targeted vagus nerve stimulation to help relieve pain and regulate chronic inflammation. The Lund-based company builds on decades of neuroimmunology research, including Kevin Tracey’s discovery of the inflammatory reflex, and is translating that work into a drug-free approach delivered through the ear’s cymba conchae. Its investigational device remains under clinical and regulatory evaluation.
Galvani BioelectronicsGalvani Bioelectronics is a clinical-stage company developing bioelectronic medicines through implant-based direct modulation of specific neural signals to organs central in chronic disease. The company's lead therapy targets Rheumatoid Arthritis via splenic nerve stimulation using a minimally invasive, laparoscopically implanted neuromodulation platform.UPPER PROVIDENCE, PA
CriterionMedFounded in 1993 by Dr. Langheier, CriterionMed develops electromedical devices and other non-invasive solutions for chronic pain management and rehabilitation. The company carries a family medical tradition reaching back to 1884 and says its products have treated more than 150,000 patients since 2002, helping people manage pain at home without relying solely on prescription drugs.NEW YORK, NY
ReBuilder Medical, IncReBuilder Medical develops the ReBuilder®, a prescription, FDA-cleared electrical stimulation device for at-home management of neuropathy and other chronic pain. Inventor and founder David B. Phillips created the original system for his father more than 30 years ago, and the company has continued producing and updating it since 1988. Based in Charles Town, West Virginia, ReBuilder Medical also supports physicians and veterans using the device in clinical and home-care settings.CHARLES TOWN, WV
BioElectronics CorporationFounded by Andrew J. Whelan in 2000, Frederick-based BioElectronics Corporation develops and manufactures wearable, drug-free electroceutical devices that use pulsed shortwave therapy for pain management. The company operates as an OEM and works with commercial and international partners to bring its ActiPatch and RecoveryRx devices to consumer and clinical markets, with four FDA 510(k) clearances and published randomized clinical research supporting its technology.JEFFERSON, MD