Doyle Organics develops plant-based crop treatments for growers seeking alternatives to conventional chemical pest control. Its formulations use natural plant defenses to help protect crops while keeping pollinators present and supporting healthier soil.
Scioto AgriTechBuilt around membrane-translocation technology developed by Ohio State University scientists, Scioto AgriTech creates biological crop treatments designed to move inside plants, where they activate immunity and suppress pests and pathogens. The Ohio company’s pipeline includes biostimulants and biologically based disease treatments for high-value fruits and vegetables, with an emphasis on reducing reliance on synthetic agricultural chemicals without genetically modifying crops. In 2024, Scioto AgriTech received a $200,000 Ohio Third Frontier grant to support commercialization of its licensed technology.COLUMBUS, OH
BioLogic Company, IncSince 1985, BioLogic Company has produced all-natural pest-control products built around beneficial nematodes, microscopic predators that target insect pests while remaining safe for people, pets, and plants. The Willow Hill, Pennsylvania company sells directly produced nematodes rather than reselling them, with its own research informing application rates and handling designed to keep the live product healthy and active. BioLogic also helps customers identify pests and choose natural treatments.WILLOW HILL, PA
Benesafe Solutions LLCFounded by Esther Salata, Benesafe Solutions makes plant-based backyard bug-barrier sprays for people, pets and outdoor spaces. Its formulas use cedarwood and citronella oils to target mosquitoes, fleas and ticks while reflecting Salata’s concern for wildlife, soil and water. The company presents itself as a small business built around making outdoor pest control simpler and less reliant on harsh chemicals.
BioWorks, IncFrom its Victor, New York base, BioWorks develops biological plant-health products and programs for horticulture and specialty agriculture growers. Its RootShield family is labeled for organic use while also serving conventional operations, and the company supports growers with a technical-services team that includes several Ph.D. specialists. BioWorks operates as a division of BioFirst Group, a global biological pest and disease-control organization with 32 local production or distribution subsidiaries and exports to more than 70 countries.MIDDLETOWN, OH