Egalet Corporation is a fully integrated specialty pharmaceutical company developing and commercializing medicines for acute and chronic pain, with a particular focus on oral products designed to deter prescription-drug abuse. Its Guardian Technology uses physical and chemical barriers alongside tailored drug release, while the company’s manufacturing approach combines pharmaceutical production with plastic injection molding. Egalet has marketed OXAYDO and SPRIX and has described late-stage abuse-deterrent opioid candidates in its pipeline.
Adroit IncorporatedAdroit Incorporated is a specialty pharmaceutical company that revives established medicines through reformulation and the 505(b)(2) pathway, with current work centered on respiratory and pain-management therapies. Founded by experienced industry professionals, the company develops niche products using advanced delivery technologies and novel dosage forms, collaborating with universities and private research laboratories to bring them forward. Adroit manufactures all of its products domestically and operates under cGMP standards.NEWTOWN, PA
Aprecia PharmaceuticalsFounded in 2003, Mason-based Aprecia Pharmaceuticals develops and manufactures medicines using three-dimensional printing, an approach that enables novel oral drug-delivery forms. Aprecia is the first company to secure regulatory approval and commercialize a 3D-printed pharmaceutical product, Spiritam®, which is produced at its cGMP manufacturing facility. The privately held company combines formulation and manufacturing expertise with a portfolio of 126 granted patents and 52 pending patents.MASON, OH
Adare Pharma SolutionsAdare Pharma Solutions is a global contract development and manufacturing organization that develops, manufactures, and packages small-molecule medicines, with a particular focus on challenging oral dosage forms. Its technology-driven work spans formulation through commercial production, including patient-centered solutions for taste masking, customized release, and swallowing difficulties. With more than 30 years of experience, Adare has developed and manufactured over 65 products sold worldwide, supported by seven sites across the United States and Europe.VANDALIA, OH
Saptalis Pharmaceuticals, LLCFounded in 2015, Saptalis Pharmaceuticals is a privately held U.S. specialty pharmaceutical company known for developing prescription therapies in niche areas, particularly for patients who need more specialized dosage forms. Its Hauppauge, New York operation supports drug development and manufacturing for pediatric and geriatric care, including oral liquids and sterile ophthalmic products.HAUPPAUGE, NY