Facili Bio LLC uses an AI-powered drug-discovery platform and proprietary computational biology to develop new cancer treatments. The company focuses on difficult areas of oncology, pairing research into patient-specific therapies with clinical studies intended to move promising discoveries toward patients.
Duo OncologyFounded by nanoparticle and drug-delivery researchers, Pittsburgh-based Duo Oncology is a clinical-stage biotechnology company developing tumor-activated medicines for cancer treatment. Its lead program, DUO-207, is designed to simplify chemotherapy by concentrating drug activity in tumors while reducing exposure in healthy tissue.PITTSBURGH, PA
Predictive OncologyPittsburgh-based Predictive Oncology uses machine learning, human tumor data and laboratory models to support oncology drug discovery and clinical treatment decisions. Its proprietary platform draws on a privately held biobank of more than 150,000 tumor samples, while its CLIA-certified Helomics laboratory provides tumor drug-response and genomic testing alongside research support for biopharmaceutical developers.PITTSBURGH, PA
AG PharmaAG Pharma is a theranostics company developing monoclonal-antibody medicines and companion diagnostic tests for cancer-specific targets. Its proprietary biomarker discovery platform links earlier disease detection with more individualized treatment, while its pipeline includes Progranulin, a monoclonal antibody intended for research use in breast cancer and other diseases. The company’s focus is co-developing diagnostic and therapeutic products that help identify responsive patients and monitor treatment.COLUMBIA, MD
Zetagen TherapeuticsFounded in 2015, Zetagen Therapeutics is a private, clinical-stage biopharmaceutical company built around a patient-centered approach to cancer research. From its Colleen Connor Cancer Research Lab, the company develops local treatments for people with metastatic cancer affecting bone, including the investigational therapy ZetaMet, which is designed to address tumors while supporting bone repair.SYRACUSE, NY