Founded in 1950 as Fabbrica Lombarda Ammino Acidi, privately held and family-owned Flamma Group develops and manufactures small-molecule pharmaceutical ingredients for drug companies. The Italian-headquartered CDMO supports projects from early process development through commercial production, with FDA-inspected facilities in Italy and operations in the United States and China. Its quality-by-design approach and more than 100 customer audits each year reflect a company built around process understanding, controlled manufacturing, and dependable supply.
FDA Inspected cGMP Facilities
Ecovadis Certified
Halal Quality System (HQS)
Ajinomoto Bio-Pharma ServicesWith more than 40 years in small-molecule manufacturing, Ajinomoto Bio-Pharma Services develops and produces pharmaceutical APIs and intermediates for drug companies worldwide. Its CDMO capabilities span the path from preclinical work through commercialization, while on-site analytical laboratories characterize molecules and support quality testing throughout their life cycle. Through Forge Biologics, a member of Ajinomoto Bio-Pharma Services, the company also provides AAV and plasmid manufacturing from preclinical through commercial stages.COLUMBUS, OH
PharmaBlock (USA), IncPharmaBlock (USA), Inc. develops and manufactures active pharmaceutical ingredients and related materials for biotech and pharmaceutical companies, taking projects from synthetic route scouting through process development and GMP production. Its Pennsylvania operation combines process R&D and FDA-registered GMP API manufacturing in West Chester with additional chemistry R&D and laboratory space in Hatfield. The West Chester site occupies a four-acre campus with 30,000 square feet of building space, while the company’s quality system has been ISO 9001 certified since 2019.HATFIELD, PA
Pharmaceutical Manufacturing Research Services, Inc. (PMRS)Founded by Edwin R. Thompson in 1994, privately held PMRS develops and contract-manufactures pharmaceutical products from clinical supply through commercial production, with analytical and quality support under one roof. The Horsham company has grown from six employees to about 30 and has completed more than 550 projects, supporting four NDA-approved commercial products, an internationally approved product, and developmental drugs. Its 130,000-square-foot custom facility and hands-on, cross-functional staff reflect a model in which every team member is involved in each project.HORSHAM, PA
Piramal Pharma SolutionsPiramal Pharma Solutions grew from Piramal’s 1988 entry into pharmaceuticals through the acquisition of Nicholas Laboratories and is now part of Piramal Pharma Limited. Its 4,700-plus employees work across 15 sites on three continents, supporting pharmaceutical and biotech companies as a contract development and manufacturing partner throughout the drug life cycle. The company places quality at the center of its operations, with an independent quality structure and a three-tier governance process.SELLERSVILLE, PA