IDEO Skincare turns more than 30 years of neuroscience research into cellular-energy skincare, built around the patented R·M·A Complex™. The company’s approach began with Nobel-nominated neurochemist Dr. John P. Blass, who adapted research on aging brain cells into a topical formula after seeing it improve his wife’s postsurgical scar. Its Skin Memory Serum and Daily Moisturizer are designed as a two-step routine that supports mitochondrial metabolism, renewal, and the skin barrier.
Cruelty-Free
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Paraben-Free
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Dermatologist-Tested
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Motif BeautyBorn from founder Devanshi Garg’s experience with burnout, inflammation, sensitivity and rosacea, Motif Beauty makes physician-led skincare focused on long-term skin health. Developed with Stanford-educated, double board-certified dermatologist Dr. Indy Chabra, the company creates streamlined, fragrance-free routines that support the skin barrier, cellular repair and daily resilience. Its formulas are made in the USA from globally sourced ingredients, with NAD+ at the center of its skin-longevity approach.
Sesha Skin TherapyFounded in 1996 from biomedical research by Harvard- and MIT-educated scientist Dr. Dean Hsieh, Sesha Skin Therapy makes science-based professional skincare for everyday use. Its proprietary Permeation Enhancement Technology (P.E.T.®), developed over more than 30 years, is designed to carry active ingredients into the skin’s regenerative layers; the company’s U.S. lab and headquarters produce paraben-free, non-toxic products that are never tested on animals. Sesha also supports licensed estheticians through specialist treatments, products, and professional resources.WEST CHESTER, PA
RESCUE SkinRESCUE Skin develops lotion and serum formulations for advanced skincare, including stem-cell-derived skincare solutions focused on skin repair and rejuvenation.NEW YORK, NY
DR. MACRENE activesFounded around the work of dermatologist-scientist Macrene Alexiades, MD, PhD, DR. MACRENE actives makes dermatologist-developed skincare designed to bring clinical research into everyday formulas. The New York company’s products are built around its patented MA37™ multi-active technology and plant-derived ingredients, while its Manhattan and Wainscott spas extend that approach into personalized treatments. Alexiades holds BA, MD, and PhD degrees from Harvard and is dual board-certified in dermatology in the United States and European Union.NEW YORK, NY