Founded on academic research software, Instrumental Software Technologies, Inc. (ISTI) develops scientific software, monitoring systems, and instrumentation for seismology and nuclear physics. Since 1998, its scientists and software engineers have built and operated seismic networks worldwide while supporting radionuclide analysis and nuclear non-proliferation work. ISTI also coordinates development of the open-source Earthworm earthquake-processing system and has offices in North America and Europe.