Founded in 1989, Integra LifeSciences is a global medical technology leader dedicated to restoring lives through innovative products in neurosurgery and tissue reconstruction. The company is known for its gold-standard portfolio including dermal regeneration templates, dural grafts, nerve guides, and surgical instruments, trusted by healthcare professionals worldwide. Integra has grown through strategic acquisitions, including the Codman neurosurgery business in 2017 and Acclarent in 2024, expanding its reach in specialty surgery and ENT.
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Smith+NephewSmith+Nephew traces its roots to a chemist shop opened by Thomas James Smith in Hull in 1856, later becoming known for wound dressings before expanding into broader medical technology. Today, the company designs and manufactures devices that help healthcare professionals repair, regenerate and replace soft and hard tissue, with operations in about 100 countries and products used by more than 15 million patients.COLUMBIA, MD
Integer Holdings CorporationInteger Holdings Corporation develops and manufactures medical devices and components for medical device companies, with a focus on cardio and vascular, neuromodulation, and cardiac rhythm management markets. The company operates as a large contract development and manufacturing organization, combining engineering and manufacturing expertise through brands including Greatbatch Medical and Lake Region Medical. Its history spans 80 years of industry innovation and manufacturing.CLARENCE, NY
Med Surgical Instruments IncStarted as a small enterprise in the early 1950s and incorporated in 1989, Med Surgical Instruments manufactures and supplies medical devices and surgical products for hospitals, clinics, surgeons and home patients worldwide. Its work extends beyond catalog products: the company develops custom specialty instruments, provides in-house repair and restoration, and supports device manufacturers through an OEM division. Med Surgical says its products conform to ISO 9001:2008, ISO 13485, CE and WHO-GMP standards.339112COLLEGEVILLE, PA
Applied MedicalApplied Medical is a new generation medical device company founded in 1987 and headquartered in Southern California. The company designs, develops, and manufactures innovative surgical products in-house, with a vertically integrated business model and over 5,000 team members serving more than 75 countries. Applied Medical is a leading provider of breakthrough technologies for minimally invasive and general surgery, as well as specialties including bariatric, breast, cardiovascular, colorectal, gynecologic, obstetric, orthopaedic, urologic, and vascular surgery.MIDDLETOWN, NY