Incorporated in 1998, Isolation Systems, Inc. manufactures field-deployable environmental control equipment and custom support systems for military, disaster-response and medical operations. Based in North Tonawanda, the company shifted its focus to expeditionary markets in 2005 and has since supplied equipment used from Alaska to Argentina, including more than 1,000 specialized units deployed in Iraq and Afghanistan. Its engineering team is known for moving custom concepts from paper to prototype quickly, often within a month.