MedicaSafe develops smart medication systems that pair prescription drugs with secure, programmable dispensing devices and cloud-based monitoring. Its first product is designed for opioid use disorder, using pre-packaged buprenorphine/naloxone cartridges and a SmartKey to guide dosing, deter unauthorized access, and give clinicians real-time usage insight. The company says its patients took medication as prescribed on 97% of days in reported results, compared with 72% for a reference treatment-as-usual group.
iRx Reminder LLCFounded by Dr. Anthony Sterns after a decade researching dementia care, Akron-based iRx Reminder develops medication-management technology that helps patients take the right dose at the right time while keeping healthcare teams informed. Its platform pairs a cloud control center and patient apps with the iLidRx dispensing pod, which uses a simple “Hold, Place, and Tilt” motion and reports dispensing in near real time. The company’s system is used in behavioral health, pharmacies, and clinical research, with 19 customers reported using the platform and collaborations spanning institutions including the University of Michigan Cancer Center.CLEVELAND, OH
Innovative Rx SolutionsInnovative Rx Solutions was founded by husband-and-wife team Mike and Kristine Maenza, whose combined 40-plus years in long-term care and intellectual and developmental disabilities shaped the company’s focus on practical medication-management solutions. The USA-owned company serves long-term care, group homes, and inpatient facilities, developing technology that helps care teams manage medication delivery and storage more safely and efficiently. Its Titan system is manufactured in the United States, while the SmartNarc Box is made in New York State.ROCHESTER, NY
PharmAdva, LLCPharmAdva, LLC makes the MedaCube, an automated pill dispenser designed to help people take complex medication schedules correctly while keeping caregivers informed. Co-founder and neurologist Dr. Michel J. Berg invented the device for his mother, and the company’s technology grew from four University of Rochester Medical Center patents. Based in Rochester, the company says MedaCube has helped thousands of people remain independent at home and has dispensed more than 100 million pills.ROCHESTER, NY
Validose IncValidose Inc. develops smart-dose technology and a connected data platform that helps clinical-trial teams address patient non-adherence in real time. Its system combines an attachable dosing device with patient coaching, clinician monitoring, and a cloud data layer, turning dose activity and patient feedback into actionable insights. The company’s solutions support multiple drug forms and treatment areas, including ophthalmic care.BROOKLYN, NY