Founded in 2004 by physician-scientist Silviu Itescu, Mesoblast develops and manufactures allogeneic, off-the-shelf cellular medicines for severe inflammatory and tissue-damage conditions. Its proprietary mesenchymal lineage cell platform supports Ryoncil, the first FDA-approved mesenchymal stromal cell therapy, while the company advances additional therapies through operations in Australia, the United States and Singapore. Mesoblast’s manufacturing approach is designed for industrial-scale production of cryopreserved cell products without donor-recipient matching.
Innovative Cellular TherapeuticsHeadquartered in Rockville, Innovative Cellular Therapeutics is a private clinical-stage biotechnology company developing cellular immunotherapies for solid tumors. Its proprietary CoupledCAR® platform underpins individually made CAR-T therapies, including the lead GCC19CART program being studied for relapsed or refractory metastatic colorectal cancer. Founded by Larry Lei Xiao and Zoe Zhao Wu, ICT combines more than 20 years of stem-cell, cell-therapy and gene-editing experience with FDA cellular-therapy review expertise.ROCKVILLE, MD
Cook MyoSite, IncCook MyoSite, Inc., a Cook Group subsidiary established in 2002, develops muscle-derived cell therapies and manufactures human muscle cell products for research and clinical development. Based in Pittsburgh, the company also provides contract manufacturing and research services grounded in more than two decades of muscle-cell technology experience.PITTSBURGH, PA
STEMCELL TechnologiesFounded in 1993 by hematopoietic stem-cell researcher Dr. Allen Eaves, STEMCELL Technologies grew from his effort to produce standardized, cost-effective cell culture media into a global biotechnology company. Based in Vancouver and guided by its “Scientists Helping Scientists” ethos, the company supports life-science researchers worldwide with tools and expert assistance for cell-based research. Its quality management system is certified to ISO 13485:2016 and ISO 9001:2015.HARLEYSVILLE, PA
Rose BioSolutionsRose BioSolutions is an advanced therapy CDMO providing human immune and stem cells, biospecimens, plasmid DNA, viral vectors, and cell therapy manufacturing. Its integrated capabilities support research, process development, clinical manufacturing, and commercial production.