Otomagnetics is developing a magnetic injection drug-delivery platform that uses a proprietary magnetic device and biodegradable particles to move therapies non-invasively into hard-to-reach ear and eye tissues. Founded by hearing and neuroscience researcher Didier Depireux, the Gaithersburg company has demonstrated delivery to inner- and middle-ear compartments in animal models, including middle-ear delivery without puncturing the eardrum. Its multidisciplinary team includes CEO Abhita Batra and Chief Medical Officer Karen Stierman, an otolaryngologist with an electrical-engineering background.
Haystack MedicalHaystack Medical develops ultra-sharp microneedles for minimally invasive inner-ear drug delivery and diagnostics, opening access through the round window membrane. The company’s work is grounded in a 20-plus-publication research record and is led by clinicians, engineers, and scientists, including otologist Anil K. Lalwani and microscale-device experts Aykut Aksit and Jeffrey W. Kysar.SCARSDALE, NY
Enable InjectionsFounded in 2010, Cincinnati-based Enable Injections develops and manufactures enFuse, a hands-free wearable drug-delivery platform that administers large-volume medications under the skin rather than intravenously. The company combines in-house design, development, and GMP-compliant manufacturing with a patient-centered approach, and its technology now supports the FDA-approved EMPAVELI Injector and other partner-branded delivery systems.CINCINNATI, OH
Ampulis IncAmpulis is a drug-delivery company built around a team with decades of experience developing medical devices and combination products. It works with pharmaceutical companies to adapt its AFS platform for sensitive medicines, helping move treatments from feasibility through clinical builds and production.BERWYN, PA
Congruence Medical Solutions LLCBaltimore-based Congruence Medical Solutions designs, develops and supplies drug-delivery devices that add precision and usability to standard prefillable syringes and other primary containers. The company is especially known for its award-winning Microliter Dosing Syringe, developed for difficult small-volume injections and recognized with the 2019 PDA Drug Delivery Innovation Award in partnership with Santen Pharmaceutical. Its platforms also address viscous and variable-dose therapies, home injection, and drug waste from vials, including through the ELDO™ technology selected for the Johnson & Johnson Innovation–JLABS and BARDA BLUE KNIGHT program.BALTIMORE, MD