Outlook Therapeutics is a biopharmaceutical company developing and commercializing ophthalmic therapies for retinal diseases, centered on LYTENAVA™ (bevacizumab-vikg) for neovascular, or wet, age-related macular degeneration. LYTENAVA is the first and only FDA-approved ophthalmic bevacizumab formulation for wet AMD in the United States, and is also authorized for the same use in the European Union and United Kingdom. The company is building on its clinical development experience to expand access to ophthalmic bevacizumab and pursue additional retinal-disease applications.
FDA approval for LYTENAVA (bevacizumab-vikg) injection
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European Commission authorization for LYTENAVA (bevacizumab gamma)
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MHRA authorization for LYTENAVA (bevacizumab gamma)
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Galimedix Therapeutics, IncGalimedix Therapeutics is a Phase 2 clinical-stage biotechnology company developing oral and topical small-molecule therapies for neurodegenerative diseases of the eye and brain. Its lead candidate, GAL-101, targets misfolded amyloid beta before toxic oligomers form and is being studied as an eye drop for geographic atrophy, an advanced form of dry age-related macular degeneration. The company’s approach also supports planned development in glaucoma and Alzheimer’s disease, with ophthalmology commercialization backed by Théa Open Innovation.KENSINGTON, MD
OcuDyneFormed in 2013, OcuDyne is a clinical-stage medical device company developing minimally invasive therapies for age-related macular degeneration by improving blood flow to the eye. Its work grew from research linking compromised ocular perfusion with AMD progression, and its investigational OPTiC system has advanced through clinical trials in Argentina and Australia.BALTIMORE, MD
PhotoOpTxBased in Solon, Ohio, PhotoOpTx develops photobiomodulation medical devices and treatment protocols for retinal disorders, including its investigational Retilux laser therapy device for diabetic macular edema. The company’s work centers on non-pharmacological light-based approaches intended to address unmet needs in ophthalmology, with research conducted alongside organizations such as the Jaeb Center for Health Research and the DRCR Network.SOLON, OH
Northmark PharmacyDeveloped by Cincinnati Eye Institute, Northmark Pharmacy has specialized since 2013 in sterile compounded ophthalmic medications for eye-care practices, with a particular focus on Avastin prepared for intravitreal injection. The Cincinnati-based pharmacy has processed more than 10,000 Avastin syringes and works with physician oversight through its full-time pharmacy team. Northmark is PCAB-accredited for sterile compounding and a member of the International Academy of Compounding Pharmacists.BLUE ASH, OH