Phycin Inc engineers and manufactures next-generation growth factors, led by its Ultrastable™ basic fibroblast growth factor for regenerative medicine and advanced cell culture. Based in Frederick, Maryland, the company combines AI-guided protein engineering with a proprietary algae-based platform to produce animal-free, endotoxin-free growth factors. Its bFGF remains active for more than 21 days at 37°C and is designed to ease the storage and handling constraints of conventional products.
Algeline® (Reg. No. 6,103,131)
Registration
StemCultures, LLCStemCultures, LLC develops and manufactures controlled-release growth factor products for cell culture, including PLGA microbeads and hydrogel DISC devices containing growth factors. Its products support human pluripotent stem cell, neural, retinal, organoid, and other cell-culture research, with custom made-to-order growth factor products also available.ALBANY, NY
Lifeline Cell TechnologyLifeline Cell Technology develops and manufactures purified primary human cells, stem-cell products, and optimized cell-culture media for laboratory research. Its founders helped introduce normal human cell systems more than 25 years ago, and the company now operates an 8,000-square-foot laboratory and administrative facility in Frederick, Maryland as a wholly owned subsidiary of International Stem Cell Corporation. Lifeline also supports researchers through scientist-led technical assistance and an international distributor network.FREDERICK, MD
Elk BioscienceElk Bioscience makes clinical-grade pooled human platelet lysate, a xeno-free cell-culture supplement for research, regenerative medicine and cell-therapy manufacturing. Based at the Pennsylvania Biotechnology Center in Doylestown, the company produces its hPL in a proprietary GMP facility using platelet units that would otherwise have been discarded, pooling material from more than 200 U.S. donors to reduce lot-to-lot variation. Its products are GMP compliant, heparin-free and supported by an FDA Data Master File for clinical-trial use.DOYLESTOWN, PA
FUJIFILM BiosciencesFUJIFILM Biosciences manufactures and distributes cell culture media and related life-sciences products, supporting customers from early development through commercial production. The company says it has manufactured cell culture media since 1970 and operates manufacturing facilities in California and Tokyo, with production also described at its facility in Tilburg, Netherlands. Its work supports biopharmaceutical, vaccine, cell and gene therapy, and diagnostic applications.WARMINSTER, PA