Qrono Inc. is a Pittsburgh biotechnology company developing immunotherapies that harness antigen-presenting cells. Its research focuses on creating new therapies in the laboratory, with Christina Cargill, PhD, serving as head of research.
Innovative Cellular TherapeuticsHeadquartered in Rockville, Innovative Cellular Therapeutics is a private clinical-stage biotechnology company developing cellular immunotherapies for solid tumors. Its proprietary CoupledCAR® platform underpins individually made CAR-T therapies, including the lead GCC19CART program being studied for relapsed or refractory metastatic colorectal cancer. Founded by Larry Lei Xiao and Zoe Zhao Wu, ICT combines more than 20 years of stem-cell, cell-therapy and gene-editing experience with FDA cellular-therapy review expertise.ROCKVILLE, MD
Noveome Biotherapeutics, IncNoveome Biotherapeutics is a Pittsburgh-based clinical-stage biopharmaceutical company developing ST266, a non-cellular biologic derived from the secretome of cultured amnion-derived epithelial cells. Its scalable GMP process produces the investigational biologic for research and clinical development across challenging diseases and conditions, with the company describing activity in clinical and preclinical studies.PITTSBURGH, PA
Duo OncologyFounded by nanoparticle and drug-delivery researchers, Pittsburgh-based Duo Oncology is a clinical-stage biotechnology company developing tumor-activated medicines for cancer treatment. Its lead program, DUO-207, is designed to simplify chemotherapy by concentrating drug activity in tumors while reducing exposure in healthy tissue.PITTSBURGH, PA
Iovance Biotherapeutics, IncIovance Biotherapeutics develops and manufactures personalized tumor-infiltrating lymphocyte (TIL) cell therapies for people with cancer. Its 136,000-square-foot Iovance Cell Therapy Center in Philadelphia makes TIL therapy using proprietary processes, including a 22-day Gen 2 process; the company also markets Amtagvi and Proleukin.PHILADELPHIA, PA