ReVivo Medical develops spinal-surgery implants, with its CEM-Plate and CEM-Cage currently under investigation in an FDA-sanctioned first-in-human clinical trial. Based in Loudonville, the company was founded by spine surgeons and biomedical researchers to improve patient outcomes while simplifying operating-room workflow and reducing implant components. Its work is backed by 18 issued U.S., European, and Canadian patents, as listed by the company.
FDA-sanctioned first-in-human-use IDE clinical trial
Compliance program
FDAIDE
Quality certification
Omnia MedicalFounded by engineers and medical-device professionals, Morgantown, West Virginia-based Omnia Medical develops orthopedic implants for spine and interventional pain care. Its work is especially focused on sacroiliac-joint stabilization, including the PsiFGuard system, which the company describes as FDA-cleared real-time guidance technology for SI-joint detection. Omnia also develops spinal fusion and biologic solutions through surgeon collaboration, with a mission centered on safe, reproducible instrumentation and shorter operative times.MORGANTOWN, WV
Intelivation TechnologiesIntelivation Technologies presents itself as an innovation hub where surgeons and engineers develop biomedical technology for orthopedic and neurosurgical care. Based in Plymouth Meeting, Pennsylvania, the company designs and commercializes implants intended to support clinical results for patients while making procedures easier for surgeons.PLYMOUTH MEETING, PA
Altus SpineAltus Spine develops and manufactures medical devices for spinal correction surgery, pairing surgeon collaboration with in-house engineering and manufacturing in its West Chester, Pennsylvania plant. Its systems include the Sochi occiput-to-sacrum platform and the Brickyard ALIF system, with design emphasis on streamlined instrumentation and rapid response to clinical needs. The company operates under ISO 13485 regulatory requirements and has received FDA 510(k) clearances for products including Sochi and Monaco HA.WEST CHESTER, PA
Auxano MedicalBorn from 1980s NASA ion-bombardment research at Case Western Reserve University, Brecksville-based Auxano Medical develops orthopedic implants designed to improve bone integration. Founded by biomaterials researcher Dr. George Picha, the company builds its products around a patented pillared surface morphology and applies it to procedures including midfoot fusion and flatfoot correction. Its research record includes 14 issued U.S. and international patents, two peer-reviewed publications, and a team with more than 75 years of combined orthopedic experience.BRECKSVILLE, OH