Since Ed Richman founded it in 1988, Richman Chemical Inc. has built its identity around helping pharmaceutical and chemical companies use outside resources more efficiently. The Pennsylvania firm coordinates custom manufacturing projects and difficult raw-material sourcing for life-science, specialty-chemical, and emerging-technology companies, working through qualified partner facilities rather than a single plant.
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J&W PharmlabFounded in 2002, Pennsylvania-based J&W Pharmlab is a contract research organization that performs custom organic synthesis and medicinal-chemistry research for life-science clients. Its 10,000-square-foot laboratory combines PhD-led project work with proprietary chiral-resolution methods and a portfolio of more than 30,000 novel building blocks. All custom synthesis is conducted domestically, with clients communicating directly with the scientist assigned to their project.LEVITTOWN, PA
Pharmaceutical Manufacturing Research Services, Inc. (PMRS)Founded by Edwin R. Thompson in 1994, privately held PMRS develops and contract-manufactures pharmaceutical products from clinical supply through commercial production, with analytical and quality support under one roof. The Horsham company has grown from six employees to about 30 and has completed more than 550 projects, supporting four NDA-approved commercial products, an internationally approved product, and developmental drugs. Its 130,000-square-foot custom facility and hands-on, cross-functional staff reflect a model in which every team member is involved in each project.HORSHAM, PA
Smart Sourcing, IncEstablished in 1998 as a spin-off from injection-molded plastics manufacturer Electronic Hardware Corporation, Smart Sourcing, Inc. is a U.S.-owned outsourcing and consulting firm that manages product development, contract manufacturing, quality control, and logistics for companies working with global suppliers. Its New York headquarters and teams in Shanghai and Ningbo give small and midsize OEMs an on-the-ground manufacturing partner rather than a broker, with more than 40 employees overseeing factory relationships and production. The company’s roots in China sourcing have grown into full “concept to completion” support for products ranging from industrial components to consumer goods.RONKONKOMA, NY
AstaTech, IncFounded in 1996 by former pharmaceutical-company scientists, Bristol, Pennsylvania-based AstaTech develops and manufactures drug-discovery building blocks and advanced intermediates while providing chemistry CRO/CDMO services. Its in-house team includes PhD chemists, and the company supports projects from discovery through commercial-scale manufacturing for 1,000 companies worldwide. AstaTech’s catalog includes more than 250,000 compounds, with custom synthesis available from milligram quantities through 10 kilograms and bulk manufacturing extending to ton scales.BRISTOL, PA