Founded in 2017 by medical-technology entrepreneur Bill Fuller and cardiac electrophysiologist Dr. Emile Daoud, Chagrin Falls-based S4 Medical makes the esolution® device, an FDA-cleared tool that deviates the esophagus during atrial-fibrillation ablation to reduce thermal injury. The company’s product was designed by electrophysiologists for catheter-ablation workflow and is supported by clinical studies including the EASY AF trial.
FDA-cleared device indication
Compliance program
FDACLEARANCE
Quality certification
AtriCure, IncFounded in 2000 and headquartered near Cincinnati, AtriCure develops and manufactures medical devices for treating atrial fibrillation and managing pain after surgery. Its AtriClip left atrial appendage system is the most widely sold device of its kind worldwide, while its Isolator Synergy system became the first device FDA-approved for surgical treatment of persistent Afib. With more than 1,400 employees and products sold in approximately 50 countries, AtriCure also supports clinical research and professional training around its therapies.MASON, OH
PAVmed IncCo-founded in 2014 by cardiothoracic surgeons Lishan Aklog and Brian deGuzman alongside medical-device executive Michael Glennon, PAVmed is a diversified, commercial-stage medical technology company built around a shared-services model. Its clinician- and scientist-led teams develop healthcare technologies intended to improve patient care, including Lucid Diagnostics’ EsoGuard test for detecting esophageal precancer and Veris Health’s remote cancer-care platform.HORSHAM, PA
CorVitaFounded by Cincinnati healthcare and emergency-response professional Angie Buckalew, CorVita is developing a universal AED adapter that translates signals between pad connectors and multiple AED brands. Buckalew drew on more than 20 years in healthcare and emergency preparedness after seeing incompatible equipment delay treatment during cardiac emergencies. The Cincinnati innovator is pursuing FDA clearance and patent protection for its plug-and-use device.CINCINNATI, OH
ZOLL Medical CorporationZOLL Medical Corporation develops medical devices and software for emergency care, with its cardiac management division best known for the LifeVest wearable cardioverter defibrillator—the world’s first wearable defibrillator. Its cardiac solutions have supported more than one million patients over more than 20 years, while helping clinicians manage acute cardiac conditions and monitor patients beyond the hospital.PITTSBURGH, PA