Founded in Chicago Tech Park in 1997, SynChem-Formosa develops and manufactures pharmaceutical compounds as a contract development and manufacturing partner for U.S. and international clients. Now a wholly owned subsidiary of Formosa Laboratories, the company brings long-running organic synthesis experience together with Formosa’s scale-up, GMP production and injectable fill-finish capabilities. Its Chicago operation is particularly associated with small-molecule synthesis and antibody-drug conjugate work, while its ADC linker technology earned a U.S. patent in 2015.
cGMP
Compliance program
GMP
Quality certification
Pharmaceutics International, Inc. (Pii)Founded in 1994, Pharmaceutics International, Inc. (Pii) is a Hunt Valley drug product contract development and manufacturing organization that takes pharmaceutical products from early development through clinical trials and commercial production. Now part of Jabil, Pii combines more than 30 years of complex-formulation experience with a 360,000-square-foot, four-site campus and more than 300 scientists and support staff. Its GMP facilities are built for demanding work, including potent compounds, complex injectables and oral drug products, with FDA-licensed and DEA-registered operations.HUNT VALLEY, MD
AstaTech, IncFounded in 1996 by former pharmaceutical-company scientists, Bristol, Pennsylvania-based AstaTech develops and manufactures drug-discovery building blocks and advanced intermediates while providing chemistry CRO/CDMO services. Its in-house team includes PhD chemists, and the company supports projects from discovery through commercial-scale manufacturing for 1,000 companies worldwide. AstaTech’s catalog includes more than 250,000 compounds, with custom synthesis available from milligram quantities through 10 kilograms and bulk manufacturing extending to ton scales.BRISTOL, PA
Ajinomoto Bio-Pharma ServicesWith more than 40 years in small-molecule manufacturing, Ajinomoto Bio-Pharma Services develops and produces pharmaceutical APIs and intermediates for drug companies worldwide. Its CDMO capabilities span the path from preclinical work through commercialization, while on-site analytical laboratories characterize molecules and support quality testing throughout their life cycle. Through Forge Biologics, a member of Ajinomoto Bio-Pharma Services, the company also provides AAV and plasmid manufacturing from preclinical through commercial stages.COLUMBUS, OH
PharmaBlock (USA), IncPharmaBlock (USA), Inc. develops and manufactures active pharmaceutical ingredients and related materials for biotech and pharmaceutical companies, taking projects from synthetic route scouting through process development and GMP production. Its Pennsylvania operation combines process R&D and FDA-registered GMP API manufacturing in West Chester with additional chemistry R&D and laboratory space in Hatfield. The West Chester site occupies a four-acre campus with 30,000 square feet of building space, while the company’s quality system has been ISO 9001 certified since 2019.HATFIELD, PA