YMC CO., LTD. develops chromatography separation and purification technologies, making LC columns and systems while also providing contract purification services. Its distinctive focus is continuous twin-column chromatography, supported by in-house packing materials, preparative equipment, and a GMP-compliant pharmaceutical purification plant in Komatsu serving scales from milligrams to hundreds of kilograms. The Kyoto-based company also applies its separation expertise to biopharmaceuticals, peptides, proteins, and oligonucleotides.
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Daicel Chiral TechnologiesDaicel Chiral Technologies develops chiral chromatography solutions that separate optical isomers, supplying columns and separation services to pharmaceutical companies, researchers, and other life-science organizations. Daicel established the chiral chromatography industry nearly 40 years ago, and the company has provided preparative separation services for more than 25 years, from milligram-scale screening through metric-ton projects. Its technical teams also help customers select columns and develop methods for difficult enantiomer separations.WEST CHESTER, PA
Chirality Biosciences, IncChirality Biosciences develops and manufactures purer active pharmaceutical ingredients using proprietary chiral separation technology, an approach intended to reduce drug side effects at the source. The company replaces older HPLC-based processes with a faster, lower-waste manufacturing system designed to help drugmakers reach FDA-compliant production sooner.
Applied SeparationsFounded in 1987, Allentown’s privately owned Applied Separations designs supercritical-fluid systems for laboratory, pilot and production use while making sample-preparation consumables for analytical laboratories. The company has built thousands of these systems and also operates certified DNA-free cleanroom facilities for custom filling, linking its work in green-chemistry processes with specialized laboratory manufacturing. Applied Separations employs about 50 people at its five-story headquarters and has worked with customers ranging from NASA to universities and textile companies developing water-free dyeing.334516ALLENTOWN, PA
Repligen CorporationRepligen Corporation develops and manufactures bioprocessing technologies and analytical instruments for biopharmaceutical process development and manufacturing. Its global manufacturing locations produce filtration systems and membranes, chromatography columns, fluid-management products and process analytics instruments for biologics and advanced-therapy workflows.CLIFTON PARK, NY