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Founded in 2017 by University of Pennsylvania researchers John Welsh and Mark Kahn, OsciFlex develops therapies and devices for venous disease, with a focus on preventing immobility-related complications such as venous thromboembolism. The Philadelphia company draws on molecular pathology research to create improved approaches to venous care, including rapid-cycling compression technology and treatments for chronic venous insufficiency.
Since its founding in 1949,株式会社オシキリ has built its identity around rethinking the relationship between people and food through machinery. The company is known for serving Japan’s major bread factories while developing patented technologies and tailoring equipment to individual customer needs. Its work now reaches overseas customers and new fields beyond baking.
Founded by equipment-design experts, chemical engineers and chemists, Lancaster-based Osmonix develops and manufactures membrane-treatment chemistry and water-filtration products for industrial purification and separation systems. Its in-house analytical and application labs go beyond product supply, testing membranes and investigating fouling so the team can recommend or design chemistry for a specific operating problem. Osmonix also engineers anti-scalants for demanding oilfield downhole conditions and distributes its U.S.-made products globally.
OSP.com LLC is an engineering-driven infrastructure company that builds and supports fiber networks for government, utility, and commercial clients. Its outside-plant roots now extend into civil pathway work, wireless infrastructure, materials sourcing, and practical field-based research and development. The company currently performs under a multi-year government contract and builds from approved drawings with close attention to inspection, turnover, and long-term operation.
Since its 1972 beginnings as Offset Service & Sales, third-generation OSS/KROY Product Center has made signage and visual communication products for businesses, schools, healthcare facilities, and other organizations. Operated by Tracy and Michael Capizzi since 2002, the family-oriented Bridgeport company also serves as the sole source for VariQuest Visual and Kinesthetic Learning Tools in Pennsylvania, New Jersey, and Delaware. Its staff guides customers through signage projects and helps educators choose classroom supplies, with repeat relationships taking priority over one-time sales.
Founded in 2016 as an on-site repair company, Warminster’s OSSCO Group now provides diesel truck and fleet maintenance alongside heavy-equipment repair, hydraulic work, and engine machining. Its 15,000-square-foot facility has 12 service bays, while mobile units still bring repairs directly to job sites and fleet yards. The company also performs OSHA/ANSI crane and bucket-truck inspections, extending its role beyond a conventional repair shop.
From its Swiss headquarters in Lyss, Osterwalder Technology AG develops and builds electric powder presses and related production technology for powder-metallurgy parts. The company brings more than 140 years of experience to customer-specific process development, including simulation, tooling concepts and practical press testing through its Customer Solution Center. Its Osterwalder CARE service supports machine productivity with maintenance, calibration and round-the-clock technical assistance.
Oswald Cycle Works was a local bike shop in Mansfield, Pennsylvania that also built handmade bicycles. After 25 years in business, the shop has closed.
Founded in New Freedom in 2022, OTB Materials Corp develops zero-portland cement technology for faster, lower-carbon construction and infrastructure work. Its TechCement platform grew from rapid-set airstrip repair technology created for military use after 9/11, and is now applied to precast manufacturing, structural projects, and critical repairs. Co-founder and chief scientist Mike Riley brings more than 40 years in defense research and materials science, along with 11 issued and nine pending U.S. patents.
Since 1963, OTC Industrial Technologies has grown from Ohio Transmission Corporation into a national industrial partner known for helping manufacturers keep equipment running. Based in Columbus, the company supports customers through 60 branches and a team of 2,000 associates, combining engineering experience with service and repair expertise for facilities across the United States.
With a weaving history reaching back to 1560 in Lyon, France, OTEX Specialty Narrow Fabrics makes high-performance narrow fabrics and develops custom textile components for mission-critical applications. The family business, now led by fourth-generation owner Denise A. Offray, operates a research and development lab and a quality-control test lab to engineer and verify fabrics used where safety matters, including aerospace, fire protection and industrial fall protection. OTEX is certified to AS9100:2016 Revision D and ISO 9001:2015, and provides lot-specific testing data with every shipment.
Built by university students from Pittsburgh and Cleveland, Ottia makes the Maker Machine, a compact factory-in-a-box that combines 3D printing with interchangeable tools for projects such as carving, engraving and food design. The company designed its enclosed machine around approachable software, modular repairs and a roughly $500 price point, aiming to put personal manufacturing within reach of enthusiasts and educators.
Ottinger Machine Company, Inc. is a family business whose roots reach back to Gotlieb Ottinger’s nineteenth-century butchering trade and whose manufacturing story began when Malcolm Ottinger designed a better hammer mill in 1934. Now operated by Malcolm’s son, Robert, the Phoenixville company continues to make the Mighty Samson for industrial users, including rendering and plastics businesses, across the United States and Canada.
Our Home is a snack company whose family of brands produces snacks ranging from better-for-you options to indulgent favorites. The company says it operates six facilities, brings together more than 1,200 team members, and is committed to quality, flavor, and value.
For more than 30 years, Outlaw Performance has carried on a street-rod manufacturing tradition from its western Pennsylvania home. The company is distinctive for building its bodies and chassis at the same facility, giving street rodders a single source for custom and hard-to-find components.
From Pittsburgh, Ovala, Inc. makes Revive, an FDA-cleared reusable bladder-support device for women experiencing light leaks during movement, coughing, or exercise. The internally worn support is designed for up to 12 hours of use and can be washed and reused for as many as 31 days, offering an alternative to bulky disposable pads. Ovala also supplies replacement strings to keep the device ready for daily use.
Founded in 1964, Oven Industries pioneered custom industrial temperature controllers and sensors, beginning with precision components for oscillator-industry ovens. The company now designs and manufactures analog, digital, and microprocessor-based thermal-control systems in prototype and production quantities, with integrated engineering and manufacturing capabilities for applications ranging from semiconductor equipment to medical and defense systems. Its design staff also develops custom solutions when an off-the-shelf controller will not fit.
Overbore Systems is an American manufacturer founded to make a positive impact on the firearms industry for professional warfighters and civilian users. Its products are made in-house, including the modular SAB-R riser, with an emphasis on keeping prices accessible without sacrificing quality.
Overhead Door Corporation manufactures and supplies access products, including doors and door operators, through three operating divisions and a portfolio of brands. Founded on C.G. Johnson’s 1921 invention of the upward-acting garage door, the company also traces its innovations to the first electric garage door opener in 1926. It reports more than 4,000 employees, 16 manufacturing facilities, and headquarters in Lewisville, Texas.
Celebrating 135 years in manufacturing, Overly Door Company is known for engineering precision barrier systems around the exact demands of architects, contractors, and government customers. The company makes custom specialty doors and fixed window units, including systems built for acoustical control and security-sensitive facilities. Overly maintains ISO 9001:2015 certification for its design and manufacturing work.