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Founded in 2014 by robotic-hand tinkerer Joel Gibbard and Samantha Payne, Bristol-based Open Bionics designs and manufactures 3D-printed bionic arms for children and adults with limb differences. Its Hero Arm was the world’s first clinically approved 3D-printed bionic hand, combining custom fitting with a deliberately expressive look and access to interchangeable covers. The company works through specialist upper-limb prosthetic clinics and has developed its devices alongside the limb-difference community.
Open.Tech by Amphenol brings together Amphenol’s military and aerospace businesses to design and supply open-architecture interconnects, VPX assemblies, and related electronics for defense manufacturers. Its specialty is helping engineers build VITA- and SOSA-aligned systems, with design and manufacturing services for VPX backplanes and plug-in cards alongside rugged optical and RF solutions. The company also participates in the SOSA consortium and VITA standards community, giving its marketplace a direct connection to the open standards shaping modular defense systems.
OpenBCI is a for-profit company built around open-source technology and a community of researchers, makers, and developers exploring human-computer interaction. It creates accessible biosensing tools for neuroscience and brain-computer interfacing, including its mixed-reality Galea platform.
Opentrons Labworks, Inc. provides laboratory automation products, including the Flex and OT-2 robots. Its documentation also presents compatible hardware modules and tools for creating and running automated biology protocols.
Founded in May 2018, Operation Space designs and builds rockets through a nationwide, remotely coordinated team of college students. Unlike university-bound rocket projects, it brings students from different schools together around collaboration rather than competition, with the goal of proving what young people can accomplish through a highly technical launch. The team assembled and tested its two-stage rockets at Vanderbilt University during build week.
Founded in 1998 when Mike Lawrenson began upfitting vehicles in his garage, OPS Public Safety designs and manufactures specialized mobile workspaces and secure storage systems for law enforcement and emergency services. Based in Watertown, New York, the company grew from a local garage operation into a North American supplier of turnkey command trailers and vehicle upfits, with its first enclosed trailer built in 2016. Its systems are made locally and tailored for frontline work in demanding environments.
Formed in 2019 through the merger of Opta Minerals and SKW Metallurgie, Opta Group LP develops custom-engineered additives, specialized equipment and technical solutions for modern manufacturing. Its Carbide Industries business produces calcium carbide, whose reaction with water generates acetylene and calcium hydroxide for industrial use. With more than 900 employees and operations across four continents, the group combines global reach with on-site technical expertise.
Opta Group LP is a global industrial manufacturer formed in 2019 by the merger of Opta Minerals Inc. and SKW Metallurgie GmbH. It develops and produces custom-engineered materials and equipment for metallurgical, construction, and specialty chemical applications, with more than 1,000 employees and 35 locations across 11 countries. Its portfolio includes metallurgical treatment products, calcium carbide-based chemicals, and recycled glass materials.
Optamark Graphics began more than 30 years ago as a boutique printing shop built around technology and innovation. It is now a brand merchandising company that helps businesses manage their branded materials through custom solutions and fulfillment. The company earned consecutive Inc. Magazine rankings after reporting 1,906% growth.
Optex is a collaborative innovation hub for the flexible-packaging industry, built around an extrusion-coating pilot facility in Phoenix, New York. It gives companies a confidential setting to test new ideas and brings industry partners together for live trials and practical training.
Founded in 1985, Optical Scientific, Inc. develops and manufactures optical scintillation-based sensors, environmental monitoring solutions, automated weather stations, optical flow sensors, and precision optical instruments. Its systems measure precipitation, present weather, visibility, air and gas flow, crosswinds, and atmospheric turbulence for airports, highways, railroads, maritime operations, power plants, refineries, environmental monitoring, and other industrial and research applications.
Since 1999, Brooklyn-based Opticology has designed, engineered, and fabricated complex optical systems, with an unusual specialty in miniature assemblies built around components smaller than 3 millimeters. Its in-house optical laboratory and fabrication facility support custom prototypes, precision alignment, and one-off systems from concept through production. The company is also known for custom colored-glass filters and microdisk optical resonators made for research and advanced instrumentation.
From its Webster, New York headquarters and 450,000-square-foot manufacturing facility, OptiCool Technologies designs and builds two-phase pumped-refrigerant cooling systems for data centers. Its Delta4T™ platform uses vaporizing refrigerant as the primary heat sink, supporting rack-level cooling up to 120 kW and serving both retrofit projects and new modular facilities. Founded by CEO Mark Chaney, the company manufactures and assembles its systems in-house and supports deployments with installation and service.
Optics Technology, Inc. was established in 1986 by optical engineer Jim Anderson, whose vision was to tackle unusually demanding miniature optical work with the flexibility to make new tools when needed. The Pittsford company designs and builds precision micro-optical systems for customers ranging from university research centers to NASA and global enterprises, often taking projects from prototype to small- or medium-volume production. Its work has included a miniature aerospace shutter and a government surveillance lens assembled entirely in-house.
Known for combining regional support with global supply, Optimas OE Solutions manufactures and distributes fasteners for OEMs and other industrial manufacturers. The company serves more than 3,500 customers and produces over 400 million fasteners annually at its Wood Dale, Illinois facility, with certified quality systems supporting automotive and industrial requirements.
Optimax Systems, Inc. manufactures custom high-precision optical components, optical coatings, and optical systems. Its capabilities include conventional and CNC fabrication, freeform polishing, metrology, laser-grade optics, and engineered coating solutions for aerospace, defense, semiconductor, space, medical, and high-power laser applications.
Founded in 1985 as a family-owned business in Ellenville, New York, Optimum Window MFG Corp. manufactures custom steel windows and doors and describes itself as one of the largest and most diversified U.S. manufacturers of fire-rated and architectural steel windows. It makes products in-house at its Upstate New York facility, combining decades of fenestration experience with custom fabrication for residential, commercial, institutional, historic, governmental, and correctional projects.
For more than 40 years, OptiPro Systems has been a Rochester-area manufacturing company known for combining machine-tool expertise with hands-on engineering support. Founded in 1982, it grew from serving New York manufacturers into a U.S. builder of specialized equipment for precision optics and advanced ceramics, with an Advanced Process Development lab for difficult applications. The company also collaborates with defense agencies, universities, and national laboratories through SBIR work.
OptiTorque Technologies LLC is a Penn Yan manufacturer known for developing high-strength fastening solutions for demanding industrial applications. The company serves OEM customers and custom-engineered projects, with in-house design, production, and testing suited to both prototypes and larger runs.
Founded in 1979 by physical therapist Jim Woog, OPTP, LLC supplies therapy, fitness and wellness tools along with educational resources for clinicians and individuals. From its Minneapolis-area base, the company develops products with recognized experts, including its exclusive SenMoCOR® laser system and the extra-long PRO-ROLLER® XL Soft foam roller, while maintaining a small-business GSA contract for government purchasing.