Founded in 2006, Bellefonte-based Actuated Medical develops medical devices that improve precision access to deep brain targets, led by its NeuralGlider® platform for brain-directed therapy delivery. The company’s motion-based technology has been developed and validated over more than a decade, supporting research groups worldwide as Actuated advances applications in neurosurgery and neurotechnology. Actuated Medical operates a 20,000-square-foot facility and is ISO 13485 certified, FDA registered, and recognized as a Woman Owned Small Business.
ISO 13485:2016
FDA Registered
Registration
Woman Owned Small Business (WOSB)
Women’s Business Enterprise (WBENC)
MDSAP Participant
Compliance program
Longeviti Neuro SolutionsFounded in 2016, Baltimore-based Longeviti Neuro Solutions develops cranial implants and neurotechnology platforms for complex brain surgery. Its ClearFit® platform combines skull reconstruction with a Brain Ultrasound Interface, allowing clinicians to image the brain through the implant after surgery, while its low-profile implants are designed to restore the skull’s natural contour and accommodate neurosurgical devices. The company reports 20 U.S. patents, 36 worldwide patents, and several FDA-cleared implants brought to market since 2018.BALTIMORE, MD
NeuroWave Systems IncFormed in 2003, Beachwood-based NeuroWave Systems develops and manufactures brain-monitoring and drug-delivery medical devices for anesthesia, critical care, and military medicine. Its NeuroSENSE® monitor stands apart by displaying independent, real-time measures of anesthetic effect for each brain hemisphere, while the company also develops closed-loop systems intended to automate sedation and anesthesia delivery. NeuroWave is an ISO 13485 medical device company with expertise spanning EEG signal processing, control engineering, and medical-device software.BEACHWOOD, OH
Pulse Technologies, IncSince 1993, Pulse Technologies has grown from a precision contract manufacturer into a 250-person engineering and manufacturing company focused on medical devices. Its Quakertown team is known for developing proprietary surface technologies alongside the production of components for implantable devices, while also supporting aerospace and defense customers. Pulse operates from a 70,000-square-foot facility and maintains ISO 13485:2016, ISO 9001:2015 and AS9100D certifications.332710QUAKERTOWN, PA