AgNovos Bioscience is a medical technology company focused on bone health, developing treatments for bone disease. Its current focus is osteoporosis and its investigational OSSURE LOEP procedure, which the company says is intended to help surgeons address bone loss associated with the disease. AgNovos is headquartered in Rockville, Maryland, near Washington, D.C., and has satellite offices in New York, Frankfurt, and Dallas.
OsteoNovusLed by co-founder and orthopedic spine surgeon Anand Agarwal, OsteoNovus develops FDA-cleared moldable bone substitutes, including its NovoGro platform, for bone repair. The company’s team brings more than 90 years of combined research experience and has performed over 10,000 orthopedic surgeries; its products are made in the USA under an ISO 13485-certified quality system.TOLEDO, OH
OrthofixFounded in 1980, Orthofix is a Lewisville, Texas-based medical technology company that develops devices and biologic solutions for spine care and limb reconstruction. Its work spans reconstructive and regenerative treatment, including bone-growth therapies and the 7D FLASH Navigation System, with products used to help patients regain mobility in more than 60 countries. Orthofix also develops biologics through its in-house tissue bank in Irvine, California, and collaborations with MTF Biologics.WAYNE, PA
OsteoDxOsteoDx develops an investigational, radiation-free device that measures bone mechanics noninvasively through its Cortical Bone Mechanics Technology (CBMT™). The Athens, Ohio company was co-founded by Brian Clark, a musculoskeletal health researcher, and its platform uses controlled vibration at the forearm to assess properties such as bending stiffness and flexural rigidity. CBMT has received more than $10 million in NIH-supported research and development and is intended for research and clinical-study settings rather than routine clinical use.ATHENS, OH
Sonogen MedicalFounded by acoustics and ultrasound expert Alan Winder, Sonogen Medical develops advanced ultrasound devices for bone-fracture healing. Based in Baltimore’s Launchport medical-device incubator, the company pairs a portable 20-minute-per-day treatment device with ultrasound-based monitoring that lets patients and caregivers follow healing progress. Its technology grew from Winder’s decades of sonar and medical-ultrasound research, including work that helped commercialize an earlier ultrasonic bone-healing device.CHEVY CHASE, MD