A Frederick, Maryland molecular diagnostics company, Akonni Biosystems is known for building integrated tools that help laboratories extract and analyze genetic material. Its nearly 20,000-square-foot manufacturing facility sits near Fort Detrick, the NIH and the National Cancer Institute, and its work includes the TruTip system for streamlined nucleic-acid preparation. Akonni develops these products for clinical diagnostics and research laboratories seeking practical, high-throughput testing workflows.
Scanogen IncBaltimore-based Scanogen develops molecular diagnostic systems that detect infectious-disease biomolecules directly from body fluids, using its proprietary Single Molecule And Rapid Tethering (SMART) technology. The company is focused on a sample-to-answer platform for point-of-care testing, including an assay designed to identify bloodstream-infection pathogens from whole blood within two hours. Scanogen has received more than $20 million in NIH grants and collaborates with Johns Hopkins University and federal agencies in the Washington, D.C., area.BALTIMORE, MD
Novel Microdevices, IncBaltimore-based Novel Microdevices develops portable, sample-to-answer molecular diagnostic systems built around disposable microfluidic cartridges. Its battery-powered Novel Dx platform is designed to deliver lab-quality PCR results in about 15 minutes, including testing for respiratory infections and other diseases at the point of care. The company is establishing a GMP-compliant pilot manufacturing facility at its Baltimore headquarters to scale cartridge production.BALTIMORE, MD
ACUITYnano LLCMaryland-based ACUITYnano LLC develops biomedical and laboratory technologies that use microfluidics, optics, machine vision, and embedded control to manipulate and study nanoscale objects and living cells. Its R&D work ranges from a low-cost on-chip near-field optical microscope with reported 10-nanometer resolution to automated systems for cell and nematode analysis, including research designed for microgravity experiments. The company also helps research organizations, startups, and medical-device businesses move concepts from early development into prototypes and products.CHEVY CHASE, MD
Tetracore, IncFor more than 20 years, Rockville-based Tetracore, Inc. has developed diagnostic reagents, assays, and instruments that detect infectious diseases and biothreat agents. Its work spans human and animal health, domestic preparedness, and forensic biology, including the T-COR 8 portable PCR thermocycler and the BioThreat Alert testing platform. Tetracore’s quality system is certified to ISO 13485 and ISO 9001, with laboratories accredited to ISO/IEC 17025.ROCKVILLE, MD