Founded by scientists from Pennsylvania State University, State College-based Aleo BME develops and manufactures polymeric biomaterials for medical applications. Its nature-inspired polymer platform has produced ElaSkin® Liquid Bandage, an FDA-cleared product made at the company’s cGMP-compliant Pennsylvania facility, while its research pipeline extends into surgical adhesives and tissue repair.
cGMP-Compliant Production Facility
compliance_program
US FDA Clearance for ElaSkin Liquid Bandage
registration
Secant GroupSecant Group develops and manufactures custom biomaterials and medical textile components for implantable devices, working from early design through full-scale production. Based in Pennsylvania, the company operates more than 150,000 square feet of facilities and combines decades of textile expertise with polymer platforms such as Hydralese and PGS for drug delivery and tissue-engineering applications. Its ISO 13485:2016-certified operations include ISO 14644 Class 7 and 8 cleanrooms, supporting medical device manufacturers from startups to global companies.TELFORD, PA
ElutiaFounded by regenerative-medicine specialists C. Randal Mills and Michelle LeRoux Williams, Elutia develops biologic medical products that help implanted devices work more naturally with the body. Based in Gaithersburg, Maryland, the company builds on a proprietary drug-eluting biomaterial platform and engineered extracellular-matrix biology, with products for soft-tissue reconstruction and cardiovascular repair. Its SimpliDerm allograft and ProxiCor biomatrices are designed to support tissue integration and regeneration rather than simply provide inert structural support.GAITHERSBURG, MD
PolyGelSince its founding in 2000, PolyGel has built its identity around more than 25 years of gel-manufacturing experience and a focus on everyday well-being. Based in Pennsylvania’s Lehigh Valley, it develops soft gel materials and custom solutions for healthcare and wellness brands, including OEM and private-label partners. Its FDA- and ISO-certified facilities support work ranging from material development to finished product manufacturing.EASTON, PA
Mussel Polymers IncLaunched in 2019, Mussel Polymers Inc. is a Bethlehem specialty materials company built around a Purdue University technology that imitates how mussels adhere underwater. Its team develops Poly(Catechol-Styrene) solutions for organizations facing difficult wet-bonding problems, with work spanning industrial and biomedical applications. The company develops, tests, and produces its materials in Bethlehem, supported by analytical capabilities through Lehigh University.BETHLEHEM, PA