Founded by regenerative-medicine specialists C. Randal Mills and Michelle LeRoux Williams, Elutia develops biologic medical products that help implanted devices work more naturally with the body. Based in Gaithersburg, Maryland, the company builds on a proprietary drug-eluting biomaterial platform and engineered extracellular-matrix biology, with products for soft-tissue reconstruction and cardiovascular repair. Its SimpliDerm allograft and ProxiCor biomatrices are designed to support tissue integration and regeneration rather than simply provide inert structural support.
Aleo BME, IncFounded by scientists from Pennsylvania State University, State College-based Aleo BME develops and manufactures polymeric biomaterials for medical applications. Its nature-inspired polymer platform has produced ElaSkin® Liquid Bandage, an FDA-cleared product made at the company’s cGMP-compliant Pennsylvania facility, while its research pipeline extends into surgical adhesives and tissue repair.541714STATE COLLEGE, PA
TheradaptiveFounded by Luis M. Alvarez, whose work grew from questions raised by combat injuries, Frederick-based Theradaptive develops protein-engineering technologies for targeted tissue regeneration. Its platform creates material-binding protein variants that coat implants and carriers, including AMP2, an engineered BMP-2 variant now being evaluated in investigational spinal-fusion and dental bone-regeneration products. The company’s work spans vascular, soft-tissue, orthopedic and targeted therapeutic delivery applications.FREDERICK, MD
Viscus Biologics CorporationFounded in Cleveland in 2012, Viscus Biologics is a life-sciences product realization partner helping customers move medical technologies from early concepts into production. The company is especially known for its work with porcine-derived extracellular matrix materials, supporting regenerative-medicine researchers and medical-device developers through an ISO 13485-certified quality system.CLEVELAND, OH
US BioDesignFounded by former medical-textile company leaders Tom Molz and Skott Greenhalgh, US BioDesign develops and manufactures engineered medical textiles and implantable fabric components for medical devices. The Quakertown company specializes in braided and woven structures and operates what it describes as the world’s largest medical braider, capable of producing exceptionally small-pore braid components. Its biomedical engineers work directly with customers to develop solutions for cardiovascular, orthopedic, surgical and neurological applications, under an ISO 13485:2003-certified quality system.QUAKERTOWN, PA