Founded in Cleveland in 2012, Viscus Biologics is a life-sciences product realization partner helping customers move medical technologies from early concepts into production. The company is especially known for its work with porcine-derived extracellular matrix materials, supporting regenerative-medicine researchers and medical-device developers through an ISO 13485-certified quality system.
ISO 13485
FDA 21 CFR Part 820
Compliance program
FDA-Registered Facility
Registration
FDA
Quality certification
Smithfield BioScienceSmithfield BioScience turns traceable porcine organs, tissues and mucosa into pharmaceutical ingredients and medical-device materials at its Cincinnati, Ohio facility. Launched in 2017 as part of Smithfield Foods’ vertically integrated supply chain, the unit controls the path from hog production through processing and distribution, with trained tissue-collection specialists and on-site testing labs supporting customer specifications. It also manufactures Heparin Sodium USP/EP through a completely U.S.-based supply chain and develops additional porcine-derived applications with dedicated research and regulatory teams.CINCINNATI, OH
Vivus Technologies LLCFounded in 2014, Vivus Technologies is a family-based Medina company built around the practical knowledge of experienced tradespeople and engineers. It serves life-science research facilities with U.S.-manufactured equipment and refurbishment support, tailoring solutions to the needs of individual facilities.MEDINA, NY
Andelyn BiosciencesBorn from decades of gene-therapy research at Nationwide Children’s Hospital, Columbus-based Andelyn Biosciences is a contract development and manufacturing organization that develops and produces viral vectors and plasmids for cell and gene therapies. Spun out as an independent company in January 2020, Andelyn carries a patient-centered origin story into work spanning early development through clinical and commercial manufacturing. Its two Ohio facilities support a record that includes more than 500 cGMP clinical batches and the production experience behind an FDA-approved systemic gene therapy.COLUMBUS, OH
CollaMedix IncFounded in Cleveland in 2018 by medical-device entrepreneurs and Case Western Reserve University researchers, CollaMedix develops collagen-based medical devices using its patented electrocompaction technology. Its signature CollaFabric® is a load-bearing pure collagen fabric made from dense, aligned threads, with applications under development in tendon repair and female pelvic health. The company has received $8 million in grant funding from the National Science Foundation, National Institutes of Health, and other public entities.CLEVELAND, OH