Founded in Cleveland in 2018 by medical-device entrepreneurs and Case Western Reserve University researchers, CollaMedix develops collagen-based medical devices using its patented electrocompaction technology. Its signature CollaFabric® is a load-bearing pure collagen fabric made from dense, aligned threads, with applications under development in tendon repair and female pelvic health. The company has received $8 million in grant funding from the National Science Foundation, National Institutes of Health, and other public entities.
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Viscus Biologics CorporationFounded in Cleveland in 2012, Viscus Biologics is a life-sciences product realization partner helping customers move medical technologies from early concepts into production. The company is especially known for its work with porcine-derived extracellular matrix materials, supporting regenerative-medicine researchers and medical-device developers through an ISO 13485-certified quality system.CLEVELAND, OH
Atreon OrthopedicsDublin-based Atreon Orthopedics develops synthetic electrospun scaffolds and biologic-support devices for musculoskeletal and tissue healing. A privately owned start-up built on more than 17 years of research and development, the company’s Autobiologic™ platform is designed to work with the body’s own healing factors, with ROTIUM® used at the tendon-bone interface and related solutions extending into wound reconstruction. Atreon’s growing intellectual property portfolio includes more than 50 issued and pending patents, and its FDA-cleared ROTIUM technology has been used in more than 12,000 rotator cuff procedures.DUBLIN, OH
Aatru Medical, LLCCleveland-based Aatru Medical, LLC develops medical devices for surgical incision management, including NPSIMS, its chemical pump-based negative pressure wound therapy system. The privately held company’s device uses a patented, no-moving-parts design to provide continuous therapy for up to seven days, with an emphasis on simpler application and affordable access to care. Aatru’s leadership combines medical, scientific and technology-development experience, and the company’s clinical work has been published in PubMed Central/Cureus.CLEVELAND, OH
Maiden Biosciences, IncFounded in 2016, Maiden Biosciences is a U.S.-based small biotechnology company that distributes prescription-only collagen topical dressings for wound and post-surgical care. Its dressings use structurally intact collagen, formulated to absorb wound exudate while maintaining a moist environment, with both sheet and powder formats available for different applications. The company is located in an economically diverse HUB zone and offers products with a stated 10-year shelf life.GAITHERSBURG, MD