Dublin-based Atreon Orthopedics develops synthetic electrospun scaffolds and biologic-support devices for musculoskeletal and tissue healing. A privately owned start-up built on more than 17 years of research and development, the company’s Autobiologic™ platform is designed to work with the body’s own healing factors, with ROTIUM® used at the tendon-bone interface and related solutions extending into wound reconstruction. Atreon’s growing intellectual property portfolio includes more than 50 issued and pending patents, and its FDA-cleared ROTIUM technology has been used in more than 12,000 rotator cuff procedures.
FDA 510(k) clearance for ROTIUM
Registration
FDA 510(k) clearance for BioCharge
Registration
Trace Orthopedics LLCTrace Orthopedics is developing a device and needle-based method to reattach partially torn tendons to bone without surgery or a visit to the operating room. Founded by biomedical engineer Adam Greenspan and musculoskeletal radiologist William B. Morrison, the Philadelphia medical-device company is testing its Trace Method in a human cadaveric hip model while pursuing product development and FDA clearance. Its approach is intended to let surgeons perform tendon repair percutaneously, potentially reducing recovery time and treatment costs.PHILADELPHIA, PA
Nanofiber Solutions, LLCFounded in 2009 by technical founders Dr. John Lannutti and Dr. Jed Johnson, Dublin-based Nanofiber Solutions designs and manufactures three-dimensional nanofiber scaffolds that mimic the body’s extracellular matrix for regenerative medicine and cell research. Its platform spans off-the-shelf cell-culture products and custom scaffolds, including the company’s work toward tissue-engineered implants and bioreactor-scale applications. Nanofiber Solutions moved into a more than 12,000-square-foot Dublin facility in 2021 and received FDA clearances for products in 2018 and 2019.DUBLIN, OH
OrthofixFounded in 1980, Orthofix is a Lewisville, Texas-based medical technology company that develops devices and biologic solutions for spine care and limb reconstruction. Its work spans reconstructive and regenerative treatment, including bone-growth therapies and the 7D FLASH Navigation System, with products used to help patients regain mobility in more than 60 countries. Orthofix also develops biologics through its in-house tissue bank in Irvine, California, and collaborations with MTF Biologics.WAYNE, PA
ElutiaFounded by regenerative-medicine specialists C. Randal Mills and Michelle LeRoux Williams, Elutia develops biologic medical products that help implanted devices work more naturally with the body. Based in Gaithersburg, Maryland, the company builds on a proprietary drug-eluting biomaterial platform and engineered extracellular-matrix biology, with products for soft-tissue reconstruction and cardiovascular repair. Its SimpliDerm allograft and ProxiCor biomatrices are designed to support tissue integration and regeneration rather than simply provide inert structural support.GAITHERSBURG, MD