Aspisafe Solutions is a medical-device company founded by Talal Sharaiha, an inventor and hospital-medicine specialist who leads its work with a team spanning clinical care, engineering, and regulatory affairs. The company develops devices for critical-care patients, including tools that help clinicians manage feeding tubes and nutrition in the intensive-care setting.
Gus Gear IncBorn from founder Sarah Palya’s experience protecting her son Gus’s central line, Gus Gear develops and manufactures medical-device securement and protection products, including its flagship Central Line Vest. For more than a decade, the company has expanded that patient-informed work to support families and healthcare providers managing central lines, feeding tubes, peritoneal dialysis catheters, and ostomy bags. Its products are used in healthcare facilities across the U.S. and Canada and shipped to families worldwide.VALENCIA, PA
Respair, IncBorn from University of Pittsburgh clinical research, Pittsburgh-based Respair develops airway devices for ventilated patients, beginning with RelianceET, a breathing tube designed to replace the conventional inflatable cuff with soft baffles that seal the airway without added pressure. Founded by physicians Carl Snyderman and Garrett Coyan, the company brings surgeons, engineers, and entrepreneurs together to address ventilator-associated complications. Respair completed hundreds of benchtop tests and received a Phase I SBIR award from the NIH while advancing the device toward regulatory submission.PITTSBURGH, PA
Nursetech Medical CorpFounded in 2021 by a biomedical engineer and an ICU nurse, Nursetech Medical Corp makes the Cordflex™ bedside clip, a medical line-management device designed to keep cords, tubes, and cables organized in critical-care settings. The Dover, Delaware company develops its solutions with frontline nurses and biomedical engineers, drawing on interviews with hundreds of care professionals and real-world testing. Cordflex™ is backed by an ISO 13485 quality-management system and a granted U.S. patent.DOVER, DE
BioMedical Enterprises, IncFounded by nephrologist Alfredo Zarate, MD, BioMedical Enterprises develops medical devices aimed at difficult clinical problems, including bloodstream infections, temperature management and cancer screening. Its earlier work on hemodialysis produced a patented needle designed to reduce blood-cell damage and inflammatory-factor release, earning support from the National Institutes of Health’s commercialization program. The company’s newer devices are built around identified unmet needs and are being prepared for validation and commercialization.BETHESDA, MD