Born from University of Pittsburgh clinical research, Pittsburgh-based Respair develops airway devices for ventilated patients, beginning with RelianceET, a breathing tube designed to replace the conventional inflatable cuff with soft baffles that seal the airway without added pressure. Founded by physicians Carl Snyderman and Garrett Coyan, the company brings surgeons, engineers, and entrepreneurs together to address ventilator-associated complications. Respair completed hundreds of benchtop tests and received a Phase I SBIR award from the NIH while advancing the device toward regulatory submission.
Phase I SBIR Award from NIH
compliance_program
CircadianceFounded in 2006 near Pittsburgh by medical-device engineer David Groll, Circadiance develops and manufactures respiratory-care equipment and remote patient-monitoring systems. The company is best known for SleepWeaver, the first all-cloth positive-airway-pressure mask, and also supports infant and pediatric care through SmartMonitor and Synergy Cloud products. Circadiance is ISO 13485 certified and distributes its products internationally.EXPORT, PA
Advanced Respiratory Technologies, Inc. (ART)Founded in 2015 by extracorporeal life-support experts, Pittsburgh-based Advanced Respiratory Technologies is developing artificial lungs and a wearable Pulmonary Assist System for long-term respiratory support. Its battery-powered, 3.2-kilogram system is designed to give people with chronic lung disease greater mobility and a path home from intensive care, while also supporting military transport. ART has produced a third-generation prototype and has received more than $22 million in grant funding during its development.339113PITTSBURGH, PA
VENTSAFESan Francisco-based VENTSAFE develops mechanical ventilation devices for intensive care units, with a focus on improving respiratory support for patients in critical condition. Its ongoing development work incorporates adaptive technology, artificial intelligence and clinician feedback as the company advances its ventilation platform.
RightAirFormed around technology developed by pulmonologist and serial entrepreneur Jacob Brenner, MD, PhD, RightAir is an early-stage medical device company creating wearable breath-support therapy for people with respiratory disorders. The company was incubated through Penn Medicine’s Center for Health Care Innovation Medical Device Accelerator, and its technology has not yet been cleared by the U.S. Food and Drug Administration.PHILADELPHIA, PA