Led by co-founder and CEO Manish Vaishya, PhD, Avation Medical is a Valencia, California medical technology company developing patient-friendly neuromodulation for people with bladder conditions. Its Vivally system provides an FDA-cleared, wearable at-home treatment for overactive bladder, supported by clinical research and digital tools for patients and providers. The company completed ISO 13485 certification and launched Vivally commercially in the United States in 2023.
FDA 510(k) K220454
ISO 13485
Registration
Actuated Medical, IncFounded in 2006, Bellefonte-based Actuated Medical develops medical devices that improve precision access to deep brain targets, led by its NeuralGlider® platform for brain-directed therapy delivery. The company’s motion-based technology has been developed and validated over more than a decade, supporting research groups worldwide as Actuated advances applications in neurosurgery and neurotechnology. Actuated Medical operates a 20,000-square-foot facility and is ISO 13485 certified, FDA registered, and recognized as a Woman Owned Small Business.BELLEFONTE, PA
ReBuilder Medical, IncReBuilder Medical develops the ReBuilder®, a prescription, FDA-cleared electrical stimulation device for at-home management of neuropathy and other chronic pain. Inventor and founder David B. Phillips created the original system for his father more than 30 years ago, and the company has continued producing and updating it since 1988. Based in Charles Town, West Virginia, ReBuilder Medical also supports physicians and veterans using the device in clinical and home-care settings.CHARLES TOWN, WV
AvionovaLed by founder and CEO Noor Haj-Tamim, a commercial astronaut candidate and bioastronautics researcher, Columbus-based Avionova brings spaceflight research to people living with balance disorders. The company develops wearable earbuds intended to steady the inner ear and reduce dizziness, using targeted cooling as a nonmedication approach.HILLIARD, OH
Avery Biomedical Devices, IncFounded by Roger Avery in the late 1960s, Avery Biomedical Devices makes implanted diaphragm pacemaker systems that stimulate the phrenic nerves to support breathing. The company’s predecessor introduced the first commercially distributed diaphragm pacemaker in 1971, and Avery has since manufactured more than 10,000 neurostimulators implanted in over 50 countries. Renamed in 2005, the Long Island manufacturer’s Spirit system has full FDA approval for adult and pediatric use and is produced under an ISO 13485 quality system.COMMACK, NY