Led by co-founder and CEO Manish Vaishya, PhD, Avation Medical is a Valencia, California medical technology company developing patient-friendly neuromodulation for people with bladder conditions. Its Vivally system provides an FDA-cleared, wearable at-home treatment for overactive bladder, supported by clinical research and digital tools for patients and providers. The company completed ISO 13485 certification and launched Vivally commercially in the United States in 2023.
FDA 510(k) K220454
certification
ISO 13485
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Actuated Medical, IncFounded in 2006, Bellefonte-based Actuated Medical develops medical devices that improve precision access to deep brain targets, led by its NeuralGlider® platform for brain-directed therapy delivery. The company’s motion-based technology has been developed and validated over more than a decade, supporting research groups worldwide as Actuated advances applications in neurosurgery and neurotechnology. Actuated Medical operates a 20,000-square-foot facility and is ISO 13485 certified, FDA registered, and recognized as a Woman Owned Small Business.BELLEFONTE, PA
ReBuilder Medical, IncReBuilder Medical develops the ReBuilder®, a prescription, FDA-cleared electrical stimulation device for at-home management of neuropathy and other chronic pain. Inventor and founder David B. Phillips created the original system for his father more than 30 years ago, and the company has continued producing and updating it since 1988. Based in Charles Town, West Virginia, ReBuilder Medical also supports physicians and veterans using the device in clinical and home-care settings.CHARLES TOWN, WV
Lungpacer Medical IncFor more than 15 years, Lungpacer Medical has developed neurostimulation technologies for critical care, including the AeroPace temporary transvenous system that activates the diaphragm to help mechanically ventilated patients regain independent breathing. The company’s work spans clinical research and engineering, with its first human diaphragm-pacing use in 2015 and FDA premarket approval for AeroPace in 2024. Based in Vancouver with U.S. operations in Exton, Pennsylvania, Lungpacer is also studying continual diaphragm stimulation through its investigational AeroNova system.EXTON, PA
AvionovaLed by founder and CEO Noor Haj-Tamim, a commercial astronaut candidate and bioastronautics researcher, Columbus-based Avionova brings spaceflight research to people living with balance disorders. The company develops wearable earbuds intended to steady the inner ear and reduce dizziness, using targeted cooling as a nonmedication approach.HILLIARD, OH