Founded by cellular biologist and human-aging scientist Dr. Kan Cao, Bluelene develops and distributes American-made skincare and hair-care products centered on patented methylene blue technology. The Bethesda-based company grew from Dr. Cao’s research into aging and childhood disease Progeria, with formulations developed in its R&D lab and applied to concerns ranging from skin aging to hair density.
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Dermatologist Tested
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Cruelty Free
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SickScience LabsSickScience Labs was founded by two PhDs in genetics and bioengineering who previously researched stem-cell production, regenerative medicine, and exosomes in cancer treatment. The biotech research company now applies that background to plant-based, exosome-based skincare and hair-growth products for people seeking noninvasive approaches to skin and scalp care.
i-On® By Dr. XiDr. Xi Huang founded i-On By Dr. Xi from decades of research into iron’s role in health and skin aging. The former NYU professor, who holds a Ph.D. in Toxicology and Applied Pharmacology and has authored more than 80 peer-reviewed publications, developed the brand’s DII® technology for skincare aimed at excess iron in the skin.
IDEO SkincareIDEO Skincare turns more than 30 years of neuroscience research into cellular-energy skincare, built around the patented R·M·A Complex™. The company’s approach began with Nobel-nominated neurochemist Dr. John P. Blass, who adapted research on aging brain cells into a topical formula after seeing it improve his wife’s postsurgical scar. Its Skin Memory Serum and Daily Moisturizer are designed as a two-step routine that supports mitochondrial metabolism, renewal, and the skin barrier.
Sesha Skin TherapyFounded in 1996 from biomedical research by Harvard- and MIT-educated scientist Dr. Dean Hsieh, Sesha Skin Therapy makes science-based professional skincare for everyday use. Its proprietary Permeation Enhancement Technology (P.E.T.®), developed over more than 30 years, is designed to carry active ingredients into the skin’s regenerative layers; the company’s U.S. lab and headquarters produce paraben-free, non-toxic products that are never tested on animals. Sesha also supports licensed estheticians through specialist treatments, products, and professional resources.WEST CHESTER, PA