Cagent Vascular develops endovascular medical devices for peripheral artery disease, centered on its Serranator balloon catheters and Serration Remodeling Therapy. Co-founded by vascular surgeon Peter Schneider and inventor Robert Giasolli, the Wayne, Pennsylvania company uses focused point force rather than conventional circumferential stretching to open arteries at low pressure. Its platform includes a purpose-built catheter for difficult pedal and critical limb-threatening ischemia cases, alongside technologies still in development.
Iatri DevicesIatri Devices is a privately held medical catheter technology company developing and commercializing catheter-based solutions for interventional critical limb ischemia and chronic limb-threatening ischemia limb-salvage revascularizations. Its BOSScsc® Crossing Support Catheter platform is designed for guidewire support and access of the peripheral vasculature, including challenging, heavily calcified peripheral lesions.DUBLIN, OH
WaveClear VascularWaveClear Vascular is developing a proprietary ultrasonic catheter platform for removing vascular blood clots and calcified occlusions. Its approach combines more than one million controlled micro-cavitations per minute with acoustic micro-streaming and catheter motion, aiming to clear vessels while preserving vessel integrity and allowing targeted drug infusion. Founded by chief biophysicist Jeffrey Vaitekunas, whose career includes more than 25 patents and work on Johnson & Johnson’s UltraCision device, the company is led by a team with deep medical-device and vascular-care experience.
VasocureVasocure is a novel therapeutics company developing peptide medicines for vascular disease, centered on Pedifin, its patented F11R blocker for neointimal disease and atherosclerosis. Founded by nephrologists and scientists involved in discovering the human F11 receptor, the company draws on more than two decades of research into vascular access failure in dialysis patients. Its 62-candidate pipeline spans nephrology, cardiology, and oncology, with Pedifin in preclinical and first-in-human studies.NEW YORK, NY
PressionFounded by Adam Salamon in 2019, Pression develops cardiovascular medical devices, led by the Wave PRO™—a compact, automated external counterpulsation system for adults with drug-refractory chronic stable angina. Its calf-only, pulse-synchronized design brings a quieter, more portable alternative to bulky legacy ECP systems, with setup taking just a few minutes. The FDA-cleared system is designed for outpatient, cardiac-rehabilitation, and community-care settings.COATESVILLE, PA