Founded by Adam Salamon in 2019, Pression develops cardiovascular medical devices, led by the Wave PRO™—a compact, automated external counterpulsation system for adults with drug-refractory chronic stable angina. Its calf-only, pulse-synchronized design brings a quieter, more portable alternative to bulky legacy ECP systems, with setup taking just a few minutes. The FDA-cleared system is designed for outpatient, cardiac-rehabilitation, and community-care settings.
FDA 510(k) Clearance
certification
Cagent VascularCagent Vascular develops endovascular medical devices for peripheral artery disease, centered on its Serranator balloon catheters and Serration Remodeling Therapy. Co-founded by vascular surgeon Peter Schneider and inventor Robert Giasolli, the Wayne, Pennsylvania company uses focused point force rather than conventional circumferential stretching to open arteries at low pressure. Its platform includes a purpose-built catheter for difficult pedal and critical limb-threatening ischemia cases, alongside technologies still in development.WAYNE, PA
PinMed IncPinMed develops high-fidelity cardiovascular monitoring systems and personalized software for clinicians, researchers, and health consumers working in demanding environments. Its flagship PELEX platform is a pocket-size, FDA-cleared diagnostic 12-lead ECG system that also supports ambulatory monitoring and wireless data transmission. The company also provides integrated research systems and custom solutions, including monitoring designed for MRI- and X-ray-guided procedures, and has been recognized with a National Innovation Award.PITTSBURGH, PA
CorVitaFounded by Cincinnati healthcare and emergency-response professional Angie Buckalew, CorVita is developing a universal AED adapter that translates signals between pad connectors and multiple AED brands. Buckalew drew on more than 20 years in healthcare and emergency preparedness after seeing incompatible equipment delay treatment during cardiac emergencies. The Cincinnati innovator is pursuing FDA clearance and patent protection for its plug-and-use device.CINCINNATI, OH
Powerful MedicalFounded in 2020 by a team that includes brothers Martin and Dr. Robert Herman, Powerful Medical develops certified AI software for cardiovascular diagnosis, centered on its PMcardio platform for rapid 12-lead ECG interpretation. Its Queen of Hearts model is designed to detect occlusive heart attacks that standard STEMI criteria can miss, while PMcardio for Organizations connects those findings to hospital and emergency-care workflows. The Bratislava-based company says its platform has analyzed more than 2.5 million ECGs and is used by over 100,000 clinicians across 150-plus hospital deployments.NEW YORK, NY