Founded by surgeons dissatisfied with conventional approaches, Caira Surgical is developing joint-replacement navigation software and radar-based tracking technology for more precise surgery. Its first product is a knee-replacement navigation system, supported by proprietary technology protected by three U.S. patents and additional pending patents. The company’s cross-functional team includes experienced surgeons, medical advisers, software engineers, and hardware specialists.
Blue Belt TechnologiesBlue Belt Technologies is a medical device company focused on improving patient care through advancing surgical instrumentation technology. The company specializes in computer-aided surgical technology and navigation for orthopedic procedures.PITTSBURGH, PA
Formae, IncFormae, Inc. develops CyborGel®, an investigational synthetic hydrogel cartilage implant system for minimally invasive knee resurfacing in progressive and post-traumatic osteoarthritis. Founded by orthopedic surgeon Kevin Mansmann, M.D., the company brings together medical, engineering, additive-manufacturing and entrepreneurial experience built through more than 25 years of research and development. CyborGel has received FDA Breakthrough Device Designation and remains limited to preclinical use while regulatory submissions and medical trials continue.DEVON, PA
Centerline BiomedicalBorn from a Cleveland Clinic collaboration, Cleveland’s Centerline Biomedical develops 3D surgical navigation technology for endovascular procedures. Founded in 2014, the company’s FDA-cleared Intra-Operative Positioning System (IOPS®) combines patient-specific imaging with sensor-equipped catheters and guidewires to provide real-time positioning while helping reduce reliance on radiation-inducing fluoroscopy. Founder and CTO Vikash Goel and his team developed the technology through a decade of work with Cleveland Clinic vascular surgeon Dr. Roy Greenberg.CLEVELAND, OH
A.M. Surgical, IncFounded in 1995 by Dr. Ather Mirza, A.M. Surgical develops high-precision devices and biologic solutions for minimally invasive skeletal and soft-tissue procedures. The company is particularly known for its STRATOS carpal tunnel release system, while its newer Allio meniscal allograft extends the Mirza-led business into small-joint resurfacing. Romi Mirza has led the company since 2001 as it has grown into a multimillion-dollar surgical-device business.SMITHTOWN, NY