For more than 50 years, CAIRE Inc. has built its identity around oxygen, developing delivery equipment for people who rely on respiratory care and for commercial users who generate gas onsite. Headquartered in Ball Ground, Georgia, the company became part of Japan’s Niterra in 2018 and continues that oxygen-focused work through its medical and AirSep commercial operations.
Inogen, IncSince 2001, Inogen has developed and makes portable oxygen concentrators for people receiving respiratory therapy, with its pulse-dose systems designed for use beyond the home. The company says it has sold or rented more than one million units worldwide and distributes its concentrators through international partners in more than 59 countries. Its current product line includes the Inogen One G5 and the newer Rove systems, supported by published clinical research and a focus on extending device service life.BROOKLYN, OH
NOVAIR USA CorporationFrom its North Tonawanda facility, NOVAIR USA manufactures on-site oxygen and nitrogen generators along with medical air, vacuum, and gas equipment for healthcare and industrial users. Part of NOVAIR Groupe, the company traces its worldwide air-and-gas manufacturing to 1977 and assembles and tests its compact oxygen generators in the United States. Its quality system is certified to ISO 9001:2015 and ISO 13485:2016, and its service team supports equipment from installation through maintenance and repair.NORTH TONAWANDA, NY
OxygeniumBorn from combat-medicine experience and an emergency physician’s response to oxygen shortages in the field, Oxygenium develops portable medical oxygen delivery systems. Its patented technology generates continuous, adjustable high-flow oxygen on demand through a chemical cartridge system, offering an alternative to explosive cylinders and power-dependent concentrators. The New York company was founded by trauma surgeon and former IDF combat physician Dr. Ben Alkahe with Ran Miron.New York, NY
Rhythm Healthcare, LLCRhythm Healthcare, formerly Lifestyle Mobility Aids, makes respiratory and durable medical equipment for care delivered at home, with portable and stationary oxygen concentrators at the center of its business. Founded in 1992, the company has grown from its mobility-aids roots into a provider-focused operation with a 60,000-square-foot distribution center in Atlanta and international operations launched in 2025. Its Rhythm Resolve program replaces qualifying oxygen equipment with brand-new units and offers zero-dollar exchanges, reflecting a distinctive focus on reducing disruption for HME providers and their patients.New York, NY