Founded in Maryland in 1991 by pharmacist and biopharmaceutics researcher Edward D. Purich, family-run ChiRhoClin develops peptide- and protein-based medicines for pancreatic and gastrointestinal disease. The company’s FDA-approved ChiRhoStim® synthetic human secretin supports pancreatic-function testing, gastrinoma diagnosis, and pancreatic imaging, while its research partnerships and grant program keep the focus on advancing pancreas science. ChiRhoClin also operates CRC Labs, an FDA-inspected cGMP laboratory with more than 50 years of combined pharmaceutical experience among its staff.
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Digestive Care, IncFounded in 1990 by scientist Dr. Tibor Sipos, Bethlehem-based Digestive Care, Inc. develops and manufactures pharmaceutical treatments for gastrointestinal disorders, including the PERTZYE pancreatic enzyme replacement therapy. The company’s work grew from Sipos’s patented microencapsulation technology for protecting digestive enzymes during gastric transit, and PERTZYE is manufactured in the USA by DCI.325412BETHLEHEM, PA
Pharmaceutics International, Inc. (Pii)Founded in 1994, Pharmaceutics International, Inc. (Pii) is a Hunt Valley drug product contract development and manufacturing organization that takes pharmaceutical products from early development through clinical trials and commercial production. Now part of Jabil, Pii combines more than 30 years of complex-formulation experience with a 360,000-square-foot, four-site campus and more than 300 scientists and support staff. Its GMP facilities are built for demanding work, including potent compounds, complex injectables and oral drug products, with FDA-licensed and DEA-registered operations.HUNT VALLEY, MD
SynChem-FormosaFounded in Chicago Tech Park in 1997, SynChem-Formosa develops and manufactures pharmaceutical compounds as a contract development and manufacturing partner for U.S. and international clients. Now a wholly owned subsidiary of Formosa Laboratories, the company brings long-running organic synthesis experience together with Formosa’s scale-up, GMP production and injectable fill-finish capabilities. Its Chicago operation is particularly associated with small-molecule synthesis and antibody-drug conjugate work, while its ADC linker technology earned a U.S. patent in 2015.AURORA, OH
Gemini PharmaceuticalsFamily-owned Gemini Pharmaceuticals has been building health and wellness products for more than 40 years from its facility in Commack, New York. Known for “Bringing Pharma Into Nutrition,” the company works with brands on dietary supplement development and contract manufacturing, with an on-site ISO 17025-accredited laboratory supporting its quality systems.COMMACK, NY