A father-and-son pharmacist team gave Formula 2 Skin Care its start in Delaware in 1988, when Mark and Sam Isabella refined a cream first made for a local pharmacy customer. The family’s product, now made near Daytona Beach, Florida, is used by people and health-care providers seeking relief for severely dry or irritated skin.
Udderly SmoothFor more than 40 years, Udderly Smooth has made pharmacist-formulated creams and lotions in the USA to moisturize and soothe rough, dry skin without a greasy feel. Its Extra Care line, developed with oncology and diabetes patients in mind, is recommended by oncology nurses and other healthcare professionals, while the original cream remains a practical everyday choice for families and active hands.SALEM, OH
Park PerfectionPark Perfection is a family-owned, dermatologist-owned skin-care company built around the Parks family in Columbus, Ohio. Board-certified dermatologist Dr. Alan J. Parks founded the brand after more than 30 years in dermatology, drawing on conversations with thousands of patients to develop formulas for unmet skin-care needs. His wife Robin and children Jason and Stefanie run the day-to-day business, while the products are made in the United States.COLUMBUS, OH
Topix Skin HealthFounded in 1981 by Stanley and Burt Shaffer, Topix Skin Health develops and manufactures science-based skin-care products through a portfolio of professional and consumer brands. Its New York-based Topiderm operation provides in-house research, development and manufacturing, supported by more than 40 scientists, including three full-time PhD microbiologists. The company’s formulas are developed with dermatologists and physicians, with products tested by more than 6,000 physicians over four decades.AMITYVILLE, NY
The Skin Care SourceThe Skin Care Source is a Pennsylvania skincare company whose management team brings more than 40 years of experience from established beauty firms. It creates and manufactures clinical skincare formulas for private-label brands, using a patented delivery system and declining animal testing of any kind.EAST NORRITON, PA