Born from co-founder Sharon Samjitsingh’s experience with severe asthma, Rochester-based Health Care Originals develops cardiopulmonary wearable systems and the software that turns respiratory data into usable insight. Its ADAMM platform supports asthma and COPD care, telemedicine, and clinical research by tracking symptoms such as cough and breathing patterns between visits as well as during remote consultations. The company’s technology has received recognition including CES 2015 honors and Innovation World Cup awards.
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LASARRUSFounded by four brothers with more than 50 years of combined professional experience, LASARRUS develops WearME, an AI-powered wearable and software system for continuous COPD monitoring and early detection. The company’s research-driven platform tracks physiological signals and gives clinicians actionable insight into changes in a patient’s condition. LASARRUS has won Intel’s 2018 design contest, received three SBIR grants, and been awarded four patents as it works toward FDA clearance.BALTIMORE, MD
CareWatchCareWatch develops wearable health-monitoring devices and remote-monitoring software that give physicians and care teams real-time patient data from anywhere. Its system tracks vital information such as oxygen levels, heart rate, and movement, while sending alerts and feeding data into PointClickCare to support remote care and billing workflows. Founded by Chris Berry and led by a team spanning medical practice and software development, the company focuses on helping patients who may not always be able to advocate for themselves.DUBLIN, OH
RTM Vital Signs LLCPhiladelphia-area medical device company RTM Vital Signs develops wearable and implantable systems that continuously monitor respiratory and cardiac health in real time. Its AI-driven RTMsense respiratory system received FDA 510(k) clearance in 2025, while the company’s cardiac monitoring technology is supported by 13 issued patents. Founded by executives Nance Dicciani and Denise Devine alongside anesthesiologist and medical-device inventor Dr. Jeff Joseph, RTM also received first prize for innovation at the 2023 American Society of Anesthesiology Conference.334510AMBLER, PA
PrO2 HealthKnown for more than 25 years of respiratory research, PrO2 Health develops respiratory muscle training technology for clinical care and athletic performance. Its connected system helps providers and researchers measure breathing-muscle function remotely, while patients use it for guided training.CLEVELAND, OH