Medicrea International SAS develops medical devices for spinal surgery, including systems for cervical and thoracolumbar applications. The company is now part of Medtronic, linking its spinal-device business to the broader Medtronic organization.
SpiTrex OrthopedicsSpiTrex Orthopedics grew from Mediliant, which began with a management buyout in 2014 and later expanded through partnerships and acquisitions in the United States and Europe. Today, it serves medical-device companies as a contract manufacturer focused on bringing orthopedic implants and instruments from concept through commercialization. Its global facilities are ISO 13485-certified and FDA registered.LANCASTER, PA
Altus SpineAltus Spine develops and manufactures medical devices for spinal correction surgery, pairing surgeon collaboration with in-house engineering and manufacturing in its West Chester, Pennsylvania plant. Its systems include the Sochi occiput-to-sacrum platform and the Brickyard ALIF system, with design emphasis on streamlined instrumentation and rapid response to clinical needs. The company operates under ISO 13485 regulatory requirements and has received FDA 510(k) clearances for products including Sochi and Monaco HA.WEST CHESTER, PA
Centinel SpineWith roots in the first prodisc implantation in 1990, Centinel Spine develops and manufactures cervical and lumbar total disc replacement devices for motion-preserving spine surgery. The West Chester company’s prodisc platform has been used in more than 300,000 implantations worldwide over 35 years, and its Match-the-Disc portfolio lets surgeons select among implant designs for patient anatomy and surgical preference. In 2025, its prodisc C Vivo and prodisc C SK systems became the first two different cervical devices approved in the United States for both one- and two-level use.WEST CHESTER, PA
Phamedica IncPhamedica Inc develops medical devices for spine and orthopedic surgery, with a focus on solutions that facilitate procedures and improve patient outcomes. Its management team brings more than 100 years of combined experience across the spine and orthopedic industry to address the field’s specialized requirements.PLAINVIEW, NY