Buffalo-based MetaQil is known for developing a purpose-built oral rinse for people experiencing dysgeusia, including patients whose taste has changed during cancer treatment. The product is proudly manufactured in Buffalo, New York at an FDA-registered facility and is made for individuals and healthcare professionals seeking relief from persistent unpleasant tastes.
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Lubricity Innovations IncBuffalo-based Lubricity Innovations makes hyaluronic-acid oral sprays for people dealing with dry mouth and cotton mouth. Its Lubricity formula creates a flavorless gel film over oral tissues, while Lubricity Xtra adds mint or strawberry flavor; both are made in the USA through the company’s You First Services manufacturing operation. Lubricity is an FDA-cleared medical device and the company supports the Sjögren’s Foundation.BUFFALO, NY
Oralmega ManufacturingOralmega Manufacturing makes private-label teeth whitening and oral wellness products for brands that want to bring a custom line to market. Its U.S.-made whitening gels are developed with dental and scientific partners, while the company handles customization from formulation and packaging through fulfillment. Based in Tonawanda, New York, Oralmega pairs low minimum orders—including custom kits starting at 10 units—with FDA registration, ISO 22716 certification, and GMP compliance.TONAWANDA, NY
Ortek-BasicBites®Founded in 1998, Ortek Therapeutics develops oral-health technologies and makes BasicBites, sugar-free soft chews designed to support enamel and the oral microbiome. The company’s work grew from a long-running collaboration with the Research Foundation for the State University of New York and Stony Brook University School of Dental Medicine, where its arginine bicarbonate and calcium carbonate technology was developed and clinically tested. Ortek also created the FDA-cleared Ortek-ECD device for early detection of occlusal cavities, while BasicBites brings its microbiome research into a daily consumer product manufactured in the United States at an FDA-registered, CGMP facility.ROSLYN HEIGHTS, NY
Mouth OffMouth Off makes dissolving chewing gum designed to eliminate bad breath in under 60 seconds. Its product is positioned as an on-the-go oral-care alternative for freshening breath throughout the day.